38675-10-4

• 常用中文名：(S)-1-((R)-2-((叔丁氧基羰基)氨基)-3-苯基丙酰基)吡咯烷-2-羧酸
• 常用英文名：Boc-D-Phe-Pro-OH
• CAS号：38675-10-4
• 分子式：C₁₉H₂₆N₂O₅
• 分子量：362.420
• 发布时间：2017-04-14 15:10:00
• 更新时间：2024-01-02 13:12:52

名称

• 中文名: 叔丁氧羰基-D-苯丙酰胺-脯氨酸
• 英文名: boc-d-phe-pro-oh
• 英文别名: BOC-N-Me-D-Phe-Pro; N-(tert-Butoxycarbonyl)-D-phenylalanyl-L-proline; BOC-D-PHE-L-PRO-OH; L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-; N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-phenylalanyl-L-proline; N-tert-butoxycarbonyl-D-phenylalanyl-L-proline; tert-butyloxycarbonyl-D-phenylalanyl-L-proline

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 594.4±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₆N₂O₅
• 分子量: 362.420
• 闪点: 313.3±30.1 °C
• 精确质量: 362.184174
• PSA: 95.94000
• LogP: 2.75
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.555
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

64471-88-1 ~86% 38675-10-4

文献：Oleksyszyn, Jozef; Boduszek, Bogdan; Kam, Chih-Min; Powers, James C. Journal of Medicinal Chemistry, 1994 , vol. 37, # 2 p. 226 - 231

18942-49-9 ~% 38675-10-4

文献：Das, Jagabandhu; Kimball; Hall, Steven E.; Han, Wen-Ching; Iwanowicz, Edwin; Lin, James; Moquin, Robert V.; Reid, Joyce A.; Sack, John S.; Malley, Mary F.; Chang, Chiehying Y.; Chong, Saeho; Wang-Iverson, David B.; Roberts, Daniel G.M.; Seiler, Steven M.; Schumacher, William A.; Ogletree, Martin L. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 1 p. 45 - 49

126251-09-0 ~% 38675-10-4

文献：Poplawski, Sarah E.; Lai, Jack H.; Sanford, David G.; Sudmeier, James L.; Wu, Wengen; Bachovchin, William W. Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2022 - 2028

16652-71-4 ~% 38675-10-4

文献：Costanzo, Michael J.; Almond Jr., Harold R.; Hecker, Leonard R.; Schott, Mary R.; Yabut, Stephen C.; Zhang, Han-Cheng; Andrade-Gordon, Patricia; Corcoran, Thomas W.; Giardino, Edward C.; Kauffman, Jack A.; Lewis, Joan M.; De Garavilla, Lawrence; Haertlein, Barbara J.; Maryanoff, Bruce E. Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 1984 - 2008

19901-50-9 ~% 38675-10-4

文献：Horton, Alexandra E.; May, Oliver S.; Elsegood, Mark R. J.; Kimber, Marc C. Synlett, 2011 , # 6 p. 797 - 800

41324-66-7 ~% 38675-10-4

文献：Das, Jagabandhu; Kimball; Hall, Steven E.; Han, Wen-Ching; Iwanowicz, Edwin; Lin, James; Moquin, Robert V.; Reid, Joyce A.; Sack, John S.; Malley, Mary F.; Chang, Chiehying Y.; Chong, Saeho; Wang-Iverson, David B.; Roberts, Daniel G.M.; Seiler, Steven M.; Schumacher, William A.; Ogletree, Martin L. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 1 p. 45 - 49

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