457948-95-7

• 常用中文名：2-(4-fluorophenyl)-N-methoxy-N-methylacetamide
• 常用英文名：2-(4-fluorophenyl)-N-methoxy-N-methylacetamide
• CAS号：457948-95-7
• 分子式：C₁₀H₁₂FNO₂
• 分子量：197.20600
• 发布时间：2017-05-25 23:17:07
• 更新时间：2024-01-14 11:36:54

名称

• 英文名: 2-(4-fluorophenyl)-N-methoxy-N-methylacetamide
• 英文别名: weinreb amide

物化性质

• 分子式: C₁₀H₁₂FNO₂
• 分子量: 197.20600
• 精确质量: 197.08500
• PSA: 29.54000
• LogP: 1.38800

合成路线

1117-97-1 405-50-5 ~83% 457948-95-7

文献：SHIONOGI and CO., LTD. Patent: EP1375486 A1, 2004 ; Location in patent: Page 135 ;

6638-79-5 459-04-1 ~96% 457948-95-7

文献：Kuethe, Jeffrey T.; Yin, Jingjun; Huffman, Mark A.; Journet, Michel Patent: US2007/15923 A1, 2007 ; Location in patent: Page/Page column 7; 8 ;

6638-79-5 405-50-5 ~% 457948-95-7

文献：Jiang, Jinlong; Bunda, Jaime L.; Doss, Geoge A.; Chicchi, Gary G.; Kurtz, Marc M.; Tsao, Kwei-Lan C.; Tong, Xinchun; Zheng, Song; Upthagrove, Alana; Samuel, Koppara; Tschirret-Guth, Richard; Kumar, Sanjeev; Wheeldon, Alan; Carlson, Emma J.; Hargreaves, Richard; Burns, Donald; Hamill, Terence; Ryan, Christine; Krause, Stephen M.; Eng, WaiSi; DeVita, Robert J.; Mills, Sander G. Journal of Medicinal Chemistry, 2009 , vol. 52, # 9 p. 3039 - 3046

34837-84-8 6638-79-5 ~% 457948-95-7

文献：Jana, Samaresh; Clements, MacK D.; Sharp, Barry K.; Zheng, Nan Organic Letters, 2010 , vol. 12, # 17 p. 3736 - 3739

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