154026-92-3

• 常用中文名：6-氯-5(s)-羟基-3-氧代己酸叔丁酯
• 常用英文名：tert-Butyl 6-Chloro-5(S)-hydroxy-3-oxohexanoate
• CAS号：154026-92-3
• 分子式：C₁₀H₁₇ClO₄
• 分子量：236.69300
• 发布时间：2018-12-24 06:33:45
• 更新时间：2026-08-05 20:45:07

名称

• 中文名: 6-氯-5(s)-羟基-3-氧代己酸叔丁酯
• 英文名: tert-butyl (5S)-6-chloro-5-hydroxy-3-oxohexanoate
• 中文别名: 瑞舒伐他汀杂质76; (S)6-氯-5-羟基-3-氧代己酸叔丁酯(瑞舒伐他汀杂质); 6-氯-5(S)-羟基-3-氧己酸叔丁基酯; (S)-6-氯-5-羟基-3-氧代己酸叔丁酯; (S)-1-BOC-5-氯-4-羟基-2-戊酮; C-5片段中间体C-1,左右; 瑞舒伐他汀杂质; 6-氯-5(S)-羟基-3-氧代己酸叔丁酯; 瑞舒伐他汀杂质83
• 英文别名: (5S)-6-Chloro-5-hydroxy-3-oxo-hexanoic Acid 1,1- Dimethylethyl Ester; (S)-6-chloro-5-hydroxy-3-oxo-hexanoic acid t-butylester; (S)-1-Boc-5-chloro-4-hydroxy-2-pentanone; (S)-tert-butyl 3-methyl-1,4-diazepane-1-carboxylate; tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate; Hexanoic acid, 6-chloro-5-hydroxy-3-oxo-, 1,1-dimethylethyl ester, (5S); tert-butyl (S)-3-methyl-1,4-diazepane-1-carboxylate; Rosuvastatin Impurity 83; 1H-1,4-DIAZEPINE-1-CARBOXYLIC ACID,HEXAHYDRO-3-METHYL-,1,1-DIMETHYLETHYL ESTER,(3S); TERT-BUTYL (S)-6-CHLORO-5-HYDROXY-3-OXOHEXANOATE; (3S)-Hexahydro-3-methyl-1H-1,4-diazepine-1-carboxylic Acid 1,1-Dimethylethyl Ester; Hexahydro-2(S)-methyl-4-(t-butoxycarboxyl)-1,4-diazepine; Tert-Butyl 6-chloro-5(S)-hydroxy-3-oxohexanoate; (S)-Tertiy-Butyl-6-Chloro-5-Hydroxy-3-Oxo Hexanoate; (S)-tert-Butyl 6-chloro-5-hydroxy-3-oxohexanoate; ert-butyl(5S)-6-chloro-5-hydroxy-3-oxohexanoate; (S)-1-BOC-3-METHYL-[1,4]DIAZEPANE; (S)-tert-butyl 6-chloro-5-hydroxy-3-oxohexanoate (Rosuvastatin Impurity）; (S)-6-Chloro-5-hydroxy-3-oxo-hexanoic acid tert-butyl ester; (5S)-6-Chloro-5-hydroxy-3-oxo-hexanoic

物化性质

• 分子式: C₁₀H₁₇ClO₄
• 分子量: 236.69300
• 精确质量: 236.08200
• PSA: 63.60000
• LogP: 1.27710
• 外观性状: 浅黄色油状液体
• 储存条件: 20°C，惰性气体

安全

• 海关编码: 2918990090

合成路线

540-88-5 10488-69-4 ~77% 154026-92-3

文献：Kaneka Corporation Patent: US6340767 B1, 2002 ; Location in patent: Example 5 ;

276249-18-4 ~70% 154026-92-3

文献：Wolberg, Michael; Hummel, Werner; Wandrey, Christian; Mueller, Michael Angewandte Chemie - International Edition, 2000 , vol. 39, # 23 p. 4306 - 4308

1694-31-1 ~% 154026-92-3

文献：Wolberg, Michael; Hummel, Werner; Mueller, Michael Chemistry - A European Journal, 2001 , vol. 7, # 21 p. 4562 - 4571

上下游产品

上游产品  4
540-88-5 10488-69-4 276249-18-4 1694-31-1
下游产品  3
154026-93-4 154026-94-5 135999-61-0

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%