944401-69-8

• 常用中文名：5-溴-2-氨基-4-氟吡啶
• 常用英文名：5-bromo-4-fluoro-pyridin-2-amine
• CAS号：944401-69-8
• 分子式：C₅H₄BrFN₂
• 分子量：191.001
• 发布时间：2018-02-22 08:00:00
• 更新时间：2025-08-25 16:34:55

名称

• 中文名: 5-溴-4-氟吡啶-2-胺
• 英文名: 5-Bromo-4-fluoropyridin-2-amine
• 英文别名: 5-bromo-4-fluoropyridin-2-amine

物化性质

• 密度: 1.8±0.1 g/cm3
• 沸点: 233.6±35.0 °C at 760 mmHg
• 分子式: C₅H₄BrFN₂
• 分子量: 191.001
• 闪点: 95.1±25.9 °C
• 精确质量: 189.954178
• PSA: 39.64000
• LogP: 2.25
• 蒸汽压: 0.1±0.5 mmHg at 25°C
• 折射率: 1.605
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

944401-77-8 ~65% 944401-69-8

文献：NOVARTIS AG Patent: WO2007/84786 A1, 2007 ; Location in patent: Page/Page column 108 ; WO 2007/084786 A1

944402-15-7 ~65% 944401-69-8

文献：NOVARTIS AG Patent: WO2007/84786 A1, 2007 ; Location in patent: Page/Page column 102 ; WO 2007/084786 A1

34941-91-8 ~% 944401-69-8

文献：UCB PHARMA S.A.; BENTLEY, Jonathan Mark; BROOKINGS, Daniel Christopher; BROWN, Julien Alistair; CAIN, Thomas Paul; CHOVATIA, Praful Tulshi; FOLEY, Anne Marie; GALLIMORE, Ellen Olivia; GLEAVE, Laura Jane; HEIFETZ, Alexander; HORSLEY, Helen Tracey; HUTCHINGS, Martin Clive; JACKSON, Victoria Elizabeth; JOHNSON, James Andrew; JOHNSTONE, Craig; KROEPLIEN, Boris; LECOMTE, Fabien Claude; LEIGH, Deborah; LOWE, Martin Alexander; MADDEN, James; PORTER, John Robert; QUINCEY, Joanna Rachel; REED, Laura Claire; REUBERSON, James Thomas; RICHARDSON, Anthony John; RICHARDSON, Sarah Emily; SELBY, Matthew Duncan; SHAW, Michael Alan; ZHU, Zhaoning Patent: WO2014/9295 A1, 2014 ;

1237535-76-0 ~% 944401-69-8

文献：UCB PHARMA S.A.; BENTLEY, Jonathan Mark; BROOKINGS, Daniel Christopher; BROWN, Julien Alistair; CAIN, Thomas Paul; CHOVATIA, Praful Tulshi; FOLEY, Anne Marie; GALLIMORE, Ellen Olivia; GLEAVE, Laura Jane; HEIFETZ, Alexander; HORSLEY, Helen Tracey; HUTCHINGS, Martin Clive; JACKSON, Victoria Elizabeth; JOHNSON, James Andrew; JOHNSTONE, Craig; KROEPLIEN, Boris; LECOMTE, Fabien Claude; LEIGH, Deborah; LOWE, Martin Alexander; MADDEN, James; PORTER, John Robert; QUINCEY, Joanna Rachel; REED, Laura Claire; REUBERSON, James Thomas; RICHARDSON, Anthony John; RICHARDSON, Sarah Emily; SELBY, Matthew Duncan; SHAW, Michael Alan; ZHU, Zhaoning Patent: WO2014/9295 A1, 2014 ;

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