20448-86-6

• 常用中文名：波那普令
• 常用英文名：3-(diethylamino)propyl 3-phenylbicyclo[2.2.1]heptane-3-carboxylate
• CAS号：20448-86-6
• 分子式：C₂₁H₃₁NO₂
• 分子量：329.47600
• 发布时间：2018-06-25 10:33:34
• 更新时间：2024-01-05 17:28:23

名称

• 中文名: 波那普令
• 英文名: 3-(diethylamino)propyl 3-phenylbicyclo[2.2.1]heptane-3-carboxylate
• 中文别名: 3-二乙氨基丙基 2-苯基双环[2.2.1]庚烷-2-羧酸酯; 波那普林
• 英文别名: Bornaprinum [INN-Latin]; Bornaprine; 2-Norbornanecarboxylic acid,2-phenyl-,3-(diethylamino)propyl ester; Sormodren; Kr 339; KR 339 [German]; 2-Phenylbicyclo(2.2.1)heptane-2-carboxylic acid,3-(diethylamino)propyl ester; Bornaprino [INN-Spanish]

物化性质

• 密度: 1.056g/cm3
• 沸点: 434.3ºC at 760mmHg
• 分子式: C₂₁H₃₁NO₂
• 分子量: 329.47600
• 精确质量: 329.23500
• PSA: 29.54000
• LogP: 4.01950
• 蒸汽压: 9.6E-08mmHg at 25°C
• 折射率: 1.535

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DT4750000 CHEMICAL NAME : Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-, 3-(diethylamino)propyl ester CAS REGISTRY NUMBER : 20448-86-6 LAST UPDATED : 199203 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H31-N-O2 MOLECULAR WEIGHT : 329.53 WISWESSER LINE NOTATION : L55 ATJ CVO3N2&2 CR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 112 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 26 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960