130636-43-0

• 常用中文名：尼非卡兰
• 常用英文名：Nifekalant Hydrochloride
• CAS号：130636-43-0
• 分子式：C₁₉H₂₈ClN₅O₅
• 分子量：441.909
• 发布时间：2018-06-20 18:59:30
• 更新时间：2025-08-22 00:34:44

名称

• 中文名: 尼非卡兰
• 英文名: Nifekalant
• 中文别名: 6-[[N-(2-羟乙基)-N-(4-硝基苯基丙基)氨基]乙基氨基]-1,3-二甲基-2,4-嘧啶二酮
• 英文别名: 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-quinone; 6-[(2-{(2-Hydroxyethyl)[3-(4-nitrophenyl)propyl]amino}ethyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride (1:1); NIFEKALANT [6-((2-((2-HYDROXYETHYL)(3-(P-NITROPHENYL)PROPYL)AMINO)ETHYL)AMINO)-1,3-DIMETHYL-URACIL]; 1,3-dimethyl-6-{2-{N-(2-hydroxyethyl)-N-[3-(4-nitrophenyl) propyl]amino}ethylamino}-2,4-(1H,3H)-pyrimidinedione; 1,3-dimethyl-6-[2-(n-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino]-2,4(1h,3h)-pyrimidinedione hydrochloride; Nifekalant HCl; 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione; Shinbit; MFCD00892243; 6-((2-((2-hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyl-uracil; 2,4(1H,3H)-Pyrimidinedione, 6-[[2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl]amino]-1,3-dimethyl-, hydrochloride (1:1); 1,3-dimethyl-6-{2-[N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino]ethylamino}-2,4(1H,3H)-pyrimidinedione; Nifekalant Hydrochloride; 6-[(2-{(2-Hydroxyethyl)[3-(4-nitrophenyl)propyl]amino}ethyl)amino]-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride (1:1); 1,3-dimethyl-6-<<2-<N-<3-(4-nitrophenyl)-propyl>-N-(hydroxyethyl)amino>ethyl>amino>-2,4(1H,3H)-pyrimidinedione

物化性质

• 密度: 1.32 g/cm3
• 沸点: 597.9ºC at 760 mmHg
• 熔点: 117.5-118.5ºC
• 分子式: C₁₉H₂₈ClN₅O₅
• 分子量: 441.909
• 闪点: 315.4ºC
• 精确质量: 441.177887
• PSA: 125.32000
• LogP: 1.72940
• 外观性状: 晶体
• 蒸汽压: 3.84E-15mmHg at 25°C

合成路线

6972-27-6 ~% 130636-43-0

文献：Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

20716-25-0 ~% 130636-43-0

文献：Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

130636-37-2 ~% 130636-43-0

文献：Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

5770-44-5 ~% 130636-43-0

文献：Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

130634-09-2 130634-04-7 ~% 130636-43-0

文献：Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

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6972-27-6 20716-25-0 5770-44-5 130634-09-2
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