117693-41-1

• 常用中文名：去克拉定糖阿奇霉素
• 常用英文名：Descladinose Azithromycin
• CAS号：117693-41-1
• 分子式：C₃₀H₅₈N₂O₉
• 分子量：590.789
• 发布时间：2018-07-21 12:04:12
• 更新时间：2024-01-05 07:21:51

名称

• 中文名: 去克拉定糖阿奇霉素
• 英文名: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,13-tetrahydro xy-3,5,6,8,10,12,14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadecan -11-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside
• 中文别名: 阿奇霉素杂质 J
• 英文别名: descladinosyl azithromycin; 3-O-decladinosyl-azithromycin; Descladinose Azithromycin; 3-decladinosyl azithromycin; Oct-3-in-1-ol; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10,13-tetrahydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranoside; 3-O-descladinosylazithromycin; 3-octyne-1-ol; 5-O-desosaminyl-9-deoxo-9a-aza-9a-methyl-9a-homoerythronolide A; descladinose; 3-Octyn-1-ol; 1-Oxa-6-azacyclopentadecan-15-one, 2-ethyl-3,4,10,13-tetrahydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14 R)-; 3-O-decladinosyl-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A; Azithromycin EP Impurity J

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 727.3±60.0 °C at 760 mmHg
• 熔点: 137-140 °C
• 分子式: C₃₀H₅₈N₂O₉
• 分子量: 590.789
• 闪点: 393.7±32.9 °C
• 精确质量: 590.414246
• PSA: 152.39000
• LogP: 2.00
• 蒸汽压: 0.0±5.4 mmHg at 25°C
• 折射率: 1.538
• 储存条件: 2-8°C， 密封

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

83905-01-5 ~95% 117693-41-1

文献：Zhang, Ling; Song, Linchen; Liu, Zhaopeng; Li, Hui; Lu, Yingdong; Li, Zerong; Ma, Shutao European Journal of Medicinal Chemistry, 2010 , vol. 45, # 3 p. 915 - 922

83905-01-5 ~% 18423-89-7 117693-41-1

文献：US6930092 B1, ; Sheet 5 ;

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