毒理学数据:
毒性系数T=2，对大白鼠的口经LD50为1225mg/kg，体重。
生态学数据:
对水是稍微有害的，不要让未稀释或大量的产品接触地下水，水道或者污水系统，若无政府许可，勿将材料排入周围环境。
CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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RG1050000
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CHEMICAL NAME :
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Octadecanoic acid, cadmium salt
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CAS REGISTRY NUMBER :
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2223-93-0
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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39
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MOLECULAR FORMULA :
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C36-H70-O4.Cd
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MOLECULAR WEIGHT :
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679.46
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WISWESSER LINE NOTATION :
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QV17 2 &-CD-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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147 mg/m3/35M
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TOXIC EFFECTS :
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Behavioral - hallucinations, distorted perceptions Gastrointestinal - nausea or vomiting Gastrointestinal - other changes
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REFERENCE :
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ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 17,308,1971
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Human
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DOSE/DURATION :
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1800 ug/m3/2Y
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TOXIC EFFECTS :
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Behavioral - hallucinations, distorted perceptions Cardiac - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
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REFERENCE :
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HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(7-9),187,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1125 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(2),98,1970
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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130 mg/m3/2H
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 17,308,1971
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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590 mg/kg
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TOXIC EFFECTS :
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Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
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REFERENCE :
-
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(7-9),187,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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42100 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 36(4),17,1992
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TYPE OF TEST :
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LC - Lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Mammal - species unspecified
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DOSE/DURATION :
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>1241 mg/m3/4H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 36(4),17,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
-
Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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3 mg/m3/4H/16W-I
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REFERENCE :
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(8),29,1968 *** REVIEWS *** ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Suspected human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 IARC Cancer Review:Group 1 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 58,119,1993 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(Cd)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,34,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-DENMARK:TWA 0.01 mg(Cd)/m3 JAN 1993 OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-INDIA:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-JAPAN:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 JAN 1993 OEL-RUSSIA:STEL 0.1 mg/m3 JAN 1993 OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 JAN 1993 OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993 OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.05 mg/m3 JAN 1993 OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg(Cd)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.04 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CADMIUM, dust and fume-air:CA lowest feasible conc. REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84457 No. of Facilities: 71 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 786 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84457 No. of Facilities: 622 (estimated) No. of Industries: 12 No. of Occupations: 16 No. of Employees: 14378 (estimated) No. of Female Employees: 2152 (estimated)
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