23239-78-3

• 常用中文名：普立地芬
• 常用英文名：Pyrrolidine,3-(diphenylmethylene)-1-ethyl-, hydrochloride (1:1)
• CAS号：23239-78-3
• 分子式：C₁₉H₂₂ClN
• 分子量：299.83800
• 发布时间：2018-08-23 13:11:31
• 更新时间：2024-03-06 18:08:52

名称

• 中文名: 普立地芬
• 英文名: 3-benzhydrylidene-1-ethylpyrrolidine,hydrochloride
• 英文别名: Pridefine hydrochloride (USAN); PRIDEFINE HYDROCHLORIDE; AHR-1118; 1-Ethyl-3-diphenylmethylenepyrrolidine hydrochloride; Pridefine; Pridefine HCl; 3-(Diphenylmethylene)-1-ethylpyrrolidine hydrochloride

物化性质

• 沸点: 396.1ºC at 760mmHg
• 分子式: C₁₉H₂₂ClN
• 分子量: 299.83800
• 闪点: 173ºC
• 精确质量: 299.14400
• PSA: 3.24000
• LogP: 4.95400
• 蒸汽压: 1.75E-06mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UY1050000 CHEMICAL NAME : Pyrrolidine, 3-diphenylmethylene-1-ethyl-, hydrochloride CAS REGISTRY NUMBER : 23239-78-3 LAST UPDATED : 199012 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C19-H21-N.Cl-H MOLECULAR WEIGHT : 299.87 WISWESSER LINE NOTATION : T5N CYTJ A2 CUYR&R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 166 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 39 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 144 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 167 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,199,1972