| 中文名 | 1,2-二哌啶基乙烷 |
|---|---|
| 英文名 | 1-(2-piperidin-1-ylethyl)piperidine |
| 中文别名 |
1,2-二哌啶-1-基乙烷
1,2-二哌啶乙烷 |
| 英文别名 |
1,2-bispiperidinoethane
1,1'-Ethylenedipiperidine EINECS 217-692-7 1,2-Dipiperidinylethane 1,2-di(N-piperidine)ethane Dipiperidinoethane 1,2-Dipiperidinoethane N,N'-1,2-dipiperidinoethane Piperidine,1'-ethylenedi 1-[2-(piperidin-1-yl)ethyl]piperidine N,N'-dipiperidylethane 1,1'-(1,2-Ethanediyl)bispiperidine 1,2-di(piperidin-1-yl)ethane Piperidine,1,1'-(1,2-ethanediyl)bis |
| 熔点 | -1--0.5 ℃ |
|---|---|
| 分子式 | C12H24N2 |
| 分子量 | 196.33200 |
| 精确质量 | 196.19400 |
| PSA | 6.48000 |
| LogP | 1.83400 |
| 蒸汽压 | 0.0094mmHg at 25°C |
| 储存条件 | 密封储存，储存于阴凉、干燥的库房。 |
| 稳定性 | 常温常压下稳定，避免与不相容材料接触。
与强氧化剂，强酸反应。 |
| 分子结构 | 1、摩尔折射率：60.58 2、摩尔体积（cm3/mol）：208.6 3、等张比容（90.2K）：504.3 4、表面张力（dyne/cm）：34.1 5、介电常数：无可用的 6、极化率（10-24cm3）：24.01 7、单一同位素质量：196.193949Da 8、标称质量：196Da 9、平均质量：196.3324Da |
| 计算化学 | 1、 疏水参数计算参考值（XlogP）：2 2、 氢键供体数量：0 3、 氢键受体数量：2 4、 可旋转化学键数量：3 5、 互变异构体数量： 6、 拓扑分子极性表面积（TPSA）：6.5 7、 重原子数量：14 8、 表面电荷：0 9、 复杂度：128 10、 同位素原子数量：0 11、 确定原子立构中心数量：0 12、 不确定原子立构中心数量：0 13、 确定化学键立构中心数量：0 14、 不确定化学键立构中心数量：0 15、 共价键单元数量：1 |
| 更多 | 1. 性状：黄色透明液体 2. 密度（g/mL,25℃）：0.91 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：-1--0.5 5. 沸点（ºC,常压）：265 6. 沸点（ºC,11mmHg）：未确定 7. 折射率(n20/D)：1.4865-1.4885 8. 闪点（ºC）：110 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（mmHg,25ºC）：未确定 12. 饱和蒸气压（kPa,25ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 |
Synonym:1,1'-(1,2-Ethanediyl)bispiperidin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Ingestion: Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Extinguishing Media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Do not get water inside containers. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Keep from contact with moist air and steam. Storage: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 1932-04-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: yellow Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 265 deg C @ 760.00mmHg Freezing/Melting Point: 1 deg C Autoignition Temperature: Not available. Flash Point: 110 deg C ( 230.00 deg F) Explosion Limits, lower: N/A Explosion Limits, upper: N/A Decomposition Temperature: Solubility in water: Specific Gravity/Density: .9160g/cm3 Molecular Formula: C12H24N2 Molecular Weight: 196.33 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, moisture, excess heat, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 1932-04-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 1,2-Dipiperidinoethane - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 1932-04-3: No information available. Canada CAS# 1932-04-3 is listed on Canada's NDSL List. CAS# 1932-04-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 1932-04-3 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
|
~87%
1932-04-3 |
| 文献：Gamzaeva; Mamedova, P. Sh.; Allakhverdieva; Velieva, G. Kh.; Akhundova; Allakhverdiev Russian Journal of Applied Chemistry, 2009 , vol. 82, # 9 p. 1577 - 1581 |
|
~79%
1932-04-3 |
| 文献：Katritzky, Alan R.; Fan, Wei-Qiang; Fu, Cong Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3209 - 3213 |
|
~86%
1932-04-3 |
| 文献：Zhao, Yaohong; Cai, Shunyou; Li, Jing; Wang, David Zhigang Tetrahedron, 2013 , vol. 69, # 38 p. 8129 - 8131 |
|
~%
1932-04-3 |
| 文献：Miyahara; Sueyoshi; Kamiya Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5557 - 5561 |
|
~35%
1932-04-3 |
| 文献：Miyahara; Sueyoshi; Kamiya Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5557 - 5561 |
|
~%
1932-04-3 |
| 文献：Bitsi, G.; Schleiffer, E.; Antoni, F.; Jenner, G. Journal of Organometallic Chemistry, 1989 , vol. 373, p. 343 - 352 |
|
~%
1932-04-3 |
| 文献：Ladenburg Chemische Berichte, 1892 , vol. 25, p. 2792 |
|
~%
1932-04-3 |
| 文献：Knorr; Hoerlein; Roth Chemische Berichte, 1905 , vol. 38, p. 3138 |
| 海关编码 | 2933399090 |
|---|---|
| 中文概述 | 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
