2982-54-9

• 常用中文名：2-(4-苄氧基-苯基)-乙胺 盐酸盐
• 常用英文名：4-BENZYLOXY-3-AMINO-A-[-BENZYL-N-(1-METHYL-2P-METHOXY PHENYL ETHER) AMINO-METHYL BENZYL ALCOHOL
• CAS号：2982-54-9
• 分子式：C₁₅H₁₈ClNO
• 分子量：263.76300
• 发布时间：2018-12-07 17:23:13
• 更新时间：2024-01-11 19:48:38

名称

• 中文名: 4-苄氧基-3-氨基-a-[-苄基-n-(1-甲基-2p-甲氧基苯酯) 氨基甲基苄醇
• 英文名: 2-(4-phenylmethoxyphenyl)ethanamine,hydrochloride
• 英文别名: 4-benzyloxy-phenethylamine hcl; O-benzyltyramine hydrochloride; 4-benzyloxy-phenethylamine hydrochloride

物化性质

• 沸点: 370.5ºC at 760 mmHg
• 分子式: C₁₅H₁₈ClNO
• 分子量: 263.76300
• 闪点: 179.6ºC
• 精确质量: 263.10800
• PSA: 35.25000
• LogP: 4.26910
• 蒸汽压: 1.1E-05mmHg at 25°C
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DA0341700 CHEMICAL NAME : Benzeneethanamine, 4-(phenylmethoxy)-, hydrochloride CAS REGISTRY NUMBER : 2982-54-9 LAST UPDATED : 199112 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C15-H17-N-O.Cl-H MOLECULAR WEIGHT : 263.79 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 129 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 39,209,1976

合成路线

182921-01-3 ~99% 2982-54-9

文献：Hart, Matthew E.; Suchland, Katherine L.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S. Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1101 - 1112

1085313-37-6 100-39-0 ~97% 2982-54-9

文献：Magnus, Nicholas A.; Astleford, Bret A.; Brennan, John; Stout, James R.; Tharp-Taylor, Roger W. Organic Process Research and Development, 2009 , vol. 13, # 2 p. 280 - 284

64318-28-1 ~% 2982-54-9

文献：Rigel Pharmaceuticals, Inc.; Goff, Dane; Payan, Donald G.; Braselmann, Sylvia Patent: US2013/237524 A1, 2013 ;

51-67-2 ~% 2982-54-9

文献：Rigel Pharmaceuticals, Inc.; Goff, Dane; Payan, Donald G.; Braselmann, Sylvia Patent: US2013/237524 A1, 2013 ;

74447-34-0 ~% 2982-54-9

文献：Battersby; Chrystal; Staunton Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 1, p. 31 - 42

74447-35-1 ~% 2982-54-9

文献：Battersby; Chrystal; Staunton Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 1, p. 31 - 42

74447-33-9 ~% 2982-54-9

文献：Battersby; Chrystal; Staunton Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 1, p. 31 - 42