401811-97-0

• 常用中文名：4-[(乙氧基羰基)甲基]-4-羟基哌啶-1-羧酸叔丁酯
• 常用英文名：tert-butyl 4-(2-ethoxy-2-oxoethyl)-4-hydroxypiperidine-1-carboxylate
• CAS号：401811-97-0
• 分子式：C₁₄H₂₅NO₅
• 分子量：287.352
• 发布时间：2018-12-31 22:02:55
• 更新时间：2024-02-01 06:01:55

名称

• 中文名: 4-[(乙氧基羰基)甲基]-4-羟基哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-(2-ethoxy-2-oxoethyl)-4-hydroxypiperidine-1-carboxylate
• 英文别名: tert-butyl 4-ethoxycarbonylmethyl-4-hydroxypiperidinecarboxylate; 2-Methyl-2-propanyl 4-(2-ethoxy-2-oxoethyl)-4-hydroxy-1-piperidinecarboxylate; 4-ethoxycarbonylmethyl-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; 4-Piperidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-4-hydroxy-, ethyl ester; tert-Butyl 4-[(ethoxycarbonyl)methyl]-4-hydroxypiperidine-1-carboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 375.9±27.0 °C at 760 mmHg
• 分子式: C₁₄H₂₅NO₅
• 分子量: 287.352
• 闪点: 181.1±23.7 °C
• 精确质量: 287.173279
• PSA: 76.07000
• LogP: 1.39
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.489

合成路线

79099-07-3 105-36-2 ~87% 401811-97-0

文献：ZALICUS PHARMACEUTICALS LTD .; PAJOUHESH , Hassan; ZHU, Yongbao; ZHOU, Yuanxi; GRIMWOOD, Mike; SIMONSON, Eric Patent: WO2011/32291 A1, 2011 ; Location in patent: Page/Page column 51-52 ; WO 2011/032291 A1

79099-07-3 141-78-6 ~% 401811-97-0

文献：Gruenenthal GmbH Patent: US2009/105290 A1, 2009 ; Location in patent: Page/Page column 30 ;