72782-05-9

• 常用中文名：beta-Funaltrexamine
• 常用英文名：beta-Funaltrexamine
• CAS号：72782-05-9
• 分子式：C₂₅H₃₀N₂O₆
• 分子量：454.51600
• 发布时间：2017-08-04 11:26:20
• 更新时间：2024-01-13 12:47:32

名称

• 英文名: methyl (E)-4-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]amino]-4-oxobut-2-enoate
• 英文别名: Naltrexone fumarate methyl ester; 2-Butenoic acid,4-(((5alpha,6beta)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl)amino)-4-oxo-,methyl ester,(E)

物化性质

• 密度: 1.43g/cm3
• 沸点: 695.2ºC at 760 mmHg
• 分子式: C₂₅H₃₀N₂O₆
• 分子量: 454.51600
• 闪点: 374.2ºC
• 精确质量: 454.21000
• PSA: 111.82000
• LogP: 1.94850
• 折射率: 1.674

合成路线

17081-97-9 67025-97-2 ~70% 72782-05-9

文献：Derrick, Jan; Lewis, John W.; Moynihan, Humphrey A.; Broadbear, Jillian; Woods, James H. Journal of Pharmacy and Pharmacology, 1996 , vol. 48, # 2 p. 192 - 196

63463-07-0 78140-66-6 ~% 72782-05-9

文献：Sayre; Larson; Fries; Takemori; Portoghese Journal of Medicinal Chemistry, 1983 , vol. 26, # 9 p. 1229 - 1235