114776-28-2
114776-28-2结构式
- 常用中文名：贝帕泛
- 常用英文名：Bepafant
- CAS号：114776-28-2
- 分子式：C23H22ClN5O2S
- 分子量：467.97100
- 发布时间：2018-06-26 18:08:05
- 更新时间：2024-04-06 10:13:45
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Bepafant, also known as WEB-2170 and STY-2108, is a platelet activating factor (PAF) antagonist potentially for the treatment of asthma. Bepafant triggered apoptosis in NB4, KG1, and NB4-MR4 cells where PTEN was expressed, but not in THP1 and U937 cells where PTEN was absent. Bepafant may produce significant anti-inflammatory effects.
| 中文名 | 贝帕泛 |
|---|---|
| 英文名 | Bepafant |
| 英文别名 |
6-(2-chlorophenyl)-8,9-dihydro-1-methyl-8-[(4-morpholinyl)carbonyl]-4H,7H-cyclopenta-[4,5]thieno-[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
Web 2170 4-((6-(o-chlorophenyl)-8,9-dihydro-1-methyl-4h,7h-cyclopenta[4,5]thieno[3,2-f]-s-triazolo[4,3-a][1,4]diazepin-8-yl)carbonyl)morpholine Bepafanto [INN-Spanish] |
| 密度 | 1.59g/cm3 |
|---|---|
| 沸点 | 744.5ºC at 760mmHg |
| 分子式 | C23H22ClN5O2S |
| 分子量 | 467.97100 |
| 闪点 | 404.1ºC |
| 精确质量 | 467.11800 |
| PSA | 100.85000 |
| LogP | 2.58870 |
| 蒸汽压 | 4.86E-22mmHg at 25°C |
| 折射率 | 1.792 |