156436-90-7

156436-90-7结构式

常用中文名：PCI-0123
常用英文名：PCI-0123
CAS号：156436-90-7
分子式：C₅₂H₇₂LuN₅O₁₄++++
分子量：1166.12000
发布时间：2017-05-23 11:39:15
更新时间：2024-02-04 11:52:15
Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc. Motexafin lutetium is structurally a pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. M otexafin lutetium is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers. It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries). It is photoactivated by 732 nm light which allows greater depth of penetration.

英文名	Motexafin Lutetium Hydrate
英文别名	Bis(acetato-O)[9,10-diethyl-20,21-bis[2-[2-(2-methoxyethoxy) ethoxy]ethoxy]-4,15-dimethyl-8,11-imino-6,3_13,16-dinitrilo -1,18-benzodiazacycloeicosine-5,14-dipropanolato-N1,N18,N23,N24,N25]Lutetium hydrate