460-07-1

• 常用中文名：N-乙炔亚胺
• 常用英文名：1-acetylaziridine
• CAS号：460-07-1
• 分子式：C₄H₇NO
• 分子量：85.10450
• 发布时间：2017-08-06 11:35:40
• 更新时间：2024-01-08 13:45:46

名称

• 中文名: N-乙炔亚胺
• 英文名: 1-(aziridin-1-yl)ethanone
• 英文别名: 1-Acetylaziridine; N-acetyl aziridine; Acetylethylenimide; N-Acetylethyleneimine; AZIRIDINE,1-ACETYL; 1-Acetyl-aziridin; Acetylethylenimine; EINECS 207-301-8; N-Acetylethylenimine; Acetylethyleneimine

物化性质

• 密度: 1.126g/cm3
• 沸点: 174.2ºC at 760mmHg
• 分子式: C₄H₇NO
• 分子量: 85.10450
• 闪点: 76.2ºC
• 精确质量: 85.05280
• PSA: 20.08000
• 蒸汽压: 1.22mmHg at 25°C
• 折射率: 1.494
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CM6300000 CHEMICAL NAME : Aziridine, 1-acetyl- CAS REGISTRY NUMBER : 460-07-1 BEILSTEIN REFERENCE NO. : 0105879 LAST UPDATED : 199701 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C4-H7-N-O MOLECULAR WEIGHT : 85.12 WISWESSER LINE NOTATION : T3NTJ AV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 78 mg/kg/26W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg/33W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg/16W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,306,1954

安全

• 海关编码: 2933990090

合成路线

151-56-4 75-36-5 ~% 460-07-1

文献：Gilead Sciences, Inc. Patent: US5952375 A1, 1999 ;

151-56-4 463-51-4 ~% 460-07-1

文献：Bestian Justus Liebigs Annalen der Chemie, 1950 , vol. 566, p. 210,231

上下游产品

上游产品  3
151-56-4 75-36-5 463-51-4
下游产品  2
1190-73-4 5417-42-5

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%