463-51-4

• 常用中文名：乙烯酮
• 常用英文名：ketene
• CAS号：463-51-4
• 分子式：C₂H₂O
• 分子量：42.03670
• 相关类别： 有机原料 醇、酚、酚醇类化合物及衍生物 无环醇
• 发布时间：2018-08-02 17:50:00
• 更新时间：2025-08-27 12:34:12
• 乙烯酮非常活泼，主要用于制造乙酐及作乙酰化试剂。与乙醇反应，生成乙酰乙酸乙酯；与溴反应，生成溴代乙酰溴；与水、乙醇、乙酸、金属有机化合物反应，分别生成乙酸、乙酸乙酯、乙酐和酮。乙烯酮是多种工业有机化学品的原料。

名称

• 中文名: 乙烯酮
• 英文名: ethenone
• 英文别名: ketene; carbometene; oxoethylene; Ethen-1-one; ethylene-oxide; Keten; methylene ketone; methyleneoxaethylene; Carbomethene

物化性质

• 密度: 0.712 g/cm3
• 沸点: -56ºC
• 熔点: -150ºC
• 分子式: C₂H₂O
• 分子量: 42.03670
• 精确质量: 42.01060
• PSA: 17.07000
• LogP: 0.00400
• 外观性状: 无色气体,带有特有的气味
• 蒸汽压: 12600mmHg at 25°C
• 折射率: 1.303
• 储存条件: 库房通风低温干燥,与氧化剂分开储运

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OA7700000 CHEMICAL NAME : Ketene CAS REGISTRY NUMBER : 463-51-4 LAST UPDATED : 199712 DATA ITEMS CITED : 30 MOLECULAR FORMULA : C2-H2-O MOLECULAR WEIGHT : 42.04 WISWESSER LINE NOTATION : OCU1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 23 ppm/30M TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,209,1949 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 200 ppm/10M TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,209,1949 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 750 ppm/10M TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,209,1949 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 53 ppm/2H TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,209,1949 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 53 ppm/2H REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,209,1949 *** REVIEWS *** ACGIH TLV-STEL 2.6 mg/m3 (1.5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.86 mg/m3 (0.5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.5 ppm (0.9 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,143,1971 OSHA PEL (Gen Indu):8H TWA 0.5 ppm (0.9 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 ppm (0.9 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 ppm (0.9 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 ppm (0.9 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 0.5 ppm (0.9 mg/m3);STEL 1.5 ppm (3 mg/m3) JAN 1993 OEL-BELGIUM:TWA 0.5 ppm (0.89 mg/m3);STEL 1.5 ppm (2.6 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-FINLAND:STEL 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-FRANCE:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.5 ppm (0.9 mg/m3);STEL 1 ppm (1.8 mg/m3) JAN 1993 OEL-TURKEY:TWA 0.5 ppm (0.9 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.5 ppm (0.9 mg/m3);STEL 1.5 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO KETENE-air:10H TWA 0.5 ppm;STEL 1.5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 41840 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 66 (estimated)

安全

• 危险品运输编码: UN 1955
• 危险类别: 2.3
• 海关编码: 2914190090

合成路线

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制备

工业制法有两种。1.乙酸热解法 乙酸蒸气在700℃左右和稍加压下，以磷酸三乙酯为催化剂，热解脱水而得。将95%（W/V）乙酸液经流量计计量加入气化器气化。气化器与10%磷酸三乙酯水溶液混合，进入高铬钢制成的管式反应器，温度控制在700±20℃进行裂解。裂解气体与氨气（稳定剂）混合，分别进入一、二、三段冷凝器，第一、二段冷凝分离含量为40%左右的稀乙酸，浓缩回收使用。第三段冷凝分离得到70%左右乙酐。冷却后的裂化气体乙烯酮，以乙酸计收率可达90%。2.丙酮热解法将丙酮蒸气通入温度为650-800℃的管子中，热解气除含乙烯酮外，还含丙酮、甲烷、乙烯和一氧化碳等，经分级冷却冷凝纯化得到成品。另外，将乙炔和氧按摩尔比2：1混合，在温度为98-107℃以硅胶为载体的 ZnO/CaO/Ag2O催化剂上停留1s，即可直接生成乙烯酮。

海关

海关编码	2914190090
中文概述	2914190090 其他不含其他含氧基的无环酮。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	2914190090 other acyclic ketones without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%