5591-33-3

• 常用中文名：碘西法酸
• 常用英文名：losefamic acid
• CAS号：5591-33-3
• 分子式：C₂₈H₂₈I₆N₄O₈
• 分子量：1309.97000
• 发布时间：2018-09-29 18:17:34
• 更新时间：2024-04-03 14:30:30

名称

• 中文名: 碘西法酸
• 英文名: 3-[[10-[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)anilino]-10-oxodecanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
• 英文别名: Acidum josefamicum; Isophthalamic acid,5,5'-(octamethylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodo; Iosefamic acid; MP 271; 5,5'-(Octamethylenebis(carbonylimino))bis(N-methyl-2,4,6-triiodoisophthalamic acid); Acido iosefamico [INN-Spanish]; Acide iosefamique [INN-French]; Acidum iosefamicum [INN-Latin]

物化性质

• 密度: 2.365g/cm3
• 沸点: 891.6ºC at 760 mmHg
• 分子式: C₂₈H₂₈I₆N₄O₈
• 分子量: 1309.97000
• 闪点: 493.1ºC
• 精确质量: 1309.62000
• PSA: 191.00000
• LogP: 8.05560
• 折射率: 1.748

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NT1998000 CHEMICAL NAME : Isophthalamic acid, 5,5'-(octamethylenebis(carbonylimino))bis(N-methyl-2, 4,6-triiodo- CAS REGISTRY NUMBER : 5591-33-3 LAST UPDATED : 199712 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C28-H28-I6-N4-O8 MOLECULAR WEIGHT : 1310.00 WISWESSER LINE NOTATION : 1MVR BI DI FI CVQ EMV8VMR BI DI FI CVQ EVM1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,964,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1576 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : INVRAV Investigative Radiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1966- Volume(issue)/page/year: 15,S248,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1120 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,964,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,964,1966