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| 中文名 | D-核糖-5-磷酸二钠盐 |
|---|---|
| 英文名 | d-ribose-5-phosphate disodium salt |
| 英文别名 |
D-Ribose 5-phosphoric acid disodium salt
D-Ribose 5-phosphate disodium salt RIBOSE-5-PHOSPHATE SODIUM SALT D-Ribose-5-phosphate disodium salt hydrate Disodium (2R,3R,4R)-4-hydroxy-1-oxo-5-(phosphonooxy)-2,3-pentanediolate sodium ribose-5-phosphate D-Ribose, 5-(dihydrogen phosphate), sodium salt (1:2) D-RIBOSE-5-PHOSPHATE,SODIUM SALT MFCD00005362 Disodium 5-O-phosphonato-D-ribose EINECS 242-140-7 D-RIBOFURANOSE 5-PHOSPHATE DISODIUM SALT D-RIBOSE-5-PHOSPHORIC ACID SODIUM SALT R-5-P-NA2 D-RIBOSE 5-PHOSPHATE DISODIUM |
| 描述 | D-Ribose 5-phosphate disodium 是戊糖磷酸途径 (PPP) 氧化分支的中间产物,是 PPP 非氧化分支的最终产物。D-Ribose 5-phosphate disodium 用于核苷酸和核酸的合成。 |
|---|---|
| 相关类别 | |
| 体外研究 | 核糖-5-磷酸通常被认为是通过氧化和非氧化戊糖磷酸途径产生的[1]。 |
| 参考文献 |
| 沸点 | 539.9ºC at 760mmHg |
|---|---|
| 分子式 | C5H9Na2O8P |
| 分子量 | 274.073 |
| 闪点 | 280.3ºC |
| 精确质量 | 273.983032 |
| PSA | 159.99000 |
| 外观性状 | powder | white |
| 蒸汽压 | 6.58E-14mmHg at 25°C |
| 储存条件 | 充氩密封0ºC以下干燥保存。 |
| 水溶解性 | H2O: 50 mg/mL, clear, colorless | Soluble in water at 50mg/ml |
| 计算化学 | 1、 疏水参数计算参考值（XlogP）：-3.8 2、 氢键供体数量：3 3、 氢键受体数量：8 4、 可旋转化学键数量：2 5、 拓扑分子极性表面积（TPSA）：142 6、 重原子数量：14 7、 表面电荷：-2 8、 复杂度：226 9、 同位素原子数量：0 10、 确定原子立构中心数量：4 11、 不确定原子立构中心数量：0 12、 确定化学键立构中心数量：0 13、 不确定化学键立构中心数量：0 14、 共价键单元数量：1 |
| 更多 | 1. 性状：结晶或白色粉末。有吸湿性。 2. 密度（ g/mL,25/4 ℃ ）：不确定
3. 相对蒸汽密度（g/mL,空气=1）：不确定 4. 熔点（ºC）：不确定 5. 沸点（ºC,常压）：不确定 6. 沸点（ºC, 5.2kPa）：不确定 7. 折射率：不确定 8. 闪点（ºC）：不确定 9. 比旋光度（º C=4, 水）：+13-+15 10. 自燃点或引燃温度（ºC）：不确定 11. 蒸气压（kPa,25ºC）：不确定 12. 饱和蒸气压（kPa,60ºC）：不确定 13. 燃烧热（KJ/mol）：不确定 14. 临界温度（ºC）：不确定 15. 临界压力（KPa）：不确定 16. 油水（辛醇/水）分配系数的对数值：不确定 17. 爆炸上限（%,V/V）：不确定 18. 爆炸下限（%,V/V）：不确定 19. 溶解性：溶于水呈无色澄明溶液。 |
Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Keep container closed when not in use. Store in a tightly closed container. Deep freeze (below -20C). Store protected from moisture. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 18265-46-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: white to light yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: soluble in water Specific Gravity/Density: Molecular Formula: C5H9Na2O8P.xH2O Molecular Weight: 274.0116 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, excess heat, strong oxidants, exposure to moist air or water. Incompatibilities with Other Materials: Oxidizing agents, moisture. Hazardous Decomposition Products: Carbon monoxide, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 18265-46-8 unlisted. LD50/LC50: Not available. Carcinogenicity: D-Ribose-5-Phosphate Disodium Salt Hydrate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 18265-46-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 18265-46-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 18265-46-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi |
|---|---|
| 安全声明 (欧洲) | S22-S24/25 |
| WGK德国 | 3 |
| 海关编码 | 2919900090 |
| 海关编码 | 2919900090 |
|---|---|
| 中文概述 | HS:2919900090 其他磷酸酯及其盐（包括乳磷酸盐）（包括它们的卤化，磺化，硝化和亚硝化衍生物） 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| 监管条件 | A.入境货物通关单 B.出境货物通关单 |
| 检验检疫 | R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验 |
| Summary | 2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0% |