256376-65-5

• 常用中文名：1-(2-氟苄基)-1H-吡唑并[3,4-B]吡啶-3-甲腈
• 常用英文名：1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile
• CAS号：256376-65-5
• 分子式：C₁₄H₉FN₄
• 分子量：252.247
• 发布时间：2016-03-10 20:04:24
• 更新时间：2024-01-08 11:53:10

名称

• 中文名: 1-(2-氟苄基)-1H-吡唑并[3,4-B]吡啶-3-甲腈
• 英文名: 1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile
• 英文别名: 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile, 1-[(2-fluorophenyl)methyl]-; 3-Cyano-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-3-carbonitrile,1-[(2-fluorophenyl)methyl]; 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 454.2±40.0 °C at 760 mmHg
• 分子式: C₁₄H₉FN₄
• 分子量: 252.247
• 闪点: 228.5±27.3 °C
• 精确质量: 252.081131
• PSA: 54.50000
• LogP: 1.93
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.663
• 储存条件: 2-8°C，干燥，密封

安全

• 危害码 (欧洲): Xi

合成路线

256376-62-2 ~99% 256376-65-5

文献：BAYER HEALTHCARE AG Patent: WO2004/9589 A1, 2004 ; Location in patent: Page/Page column 30 ;

407-25-0 256376-62-2 ~98% 256376-65-5

文献：Bayer HealthCare AG Patent: US6833364 B1, 2004 ; Location in patent: Page column 33 ;

446-48-0 956010-88-1 ~83% 256376-65-5

文献：Griebenow, Nils; Schirok, Hartmut; Mittendorf, Joachim; Straub, Alexander; Follmann, Markus; Stasch, Johannes-Peter; Knorr, Andreas; Schlemmer, Karl-Heinz; Redlich, Gorden Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1197 - 1200

51859-98-4 ~% 256376-65-5

文献：Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784

256504-39-9 ~% 256376-65-5

文献：Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784

256376-59-7 ~% 256376-65-5

文献：Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784

372-48-5 ~% 256376-65-5

文献：Griebenow, Nils; Schirok, Hartmut; Mittendorf, Joachim; Straub, Alexander; Follmann, Markus; Stasch, Johannes-Peter; Knorr, Andreas; Schlemmer, Karl-Heinz; Redlich, Gorden Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1197 - 1200

956010-87-0 ~% 256376-65-5

文献：Griebenow, Nils; Schirok, Hartmut; Mittendorf, Joachim; Straub, Alexander; Follmann, Markus; Stasch, Johannes-Peter; Knorr, Andreas; Schlemmer, Karl-Heinz; Redlich, Gorden Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1197 - 1200

1186608-79-6 ~% 256376-65-5

文献：Griebenow, Nils; Schirok, Hartmut; Mittendorf, Joachim; Straub, Alexander; Follmann, Markus; Stasch, Johannes-Peter; Knorr, Andreas; Schlemmer, Karl-Heinz; Redlich, Gorden Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1197 - 1200

上下游产品

上游产品  10
256376-62-2 407-25-0 446-48-0 956010-88-1
51859-98-4 256504-39-9 256376-59-7 372-48-5
956010-87-0 1186608-79-6
下游产品  2
256376-68-8 256376-24-6