5379-88-4

• 常用中文名：3-(Morpholinomethyl)indole
• 常用英文名：3-(Morpholinomethyl)indole
• CAS号：5379-88-4
• 分子式：C₁₃H₁₆N₂O
• 分子量：216.27900
• 发布时间：2016-12-11 14:05:56
• 更新时间：2025-09-21 09:27:23

名称

• 英文名: 4-(1H-indol-3-ylmethyl)morpholine
• 英文别名: 3-Morpholinomethyl-indol

物化性质

• 密度: 1.206g/cm3
• 沸点: 379.6ºC at 760 mmHg
• 分子式: C₁₃H₁₆N₂O
• 分子量: 216.27900
• 闪点: 183.4ºC
• 精确质量: 216.12600
• PSA: 28.26000
• LogP: 1.93800
• 折射率: 1.645

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NM1140000 CHEMICAL NAME : Indole, 3-(morpholinomethyl)- CAS REGISTRY NUMBER : 5379-88-4 BEILSTEIN REFERENCE NO. : 0193005 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H16-N2-O MOLECULAR WEIGHT : 216.31 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 55 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - excitement REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,130,1952

合成路线

110-91-8 700-06-1 ~82% 5379-88-4

文献：Hamid, M. Haniti S. A.; Allen, C. Liana; Lamb, Gareth W.; Maxwell, Aoife C.; Maytum, Hannah C.; et al. Journal of the American Chemical Society, 2009 , vol. 131, p. 1766 - 1774

110-91-8 120-72-9 50-00-0 ~87% 5379-88-4

文献：Arzephoni, Amene Yaghoubi; Naimi-Jamal, M. Reza; Sharifi, Ali; Abaee, M. Saeed; Mirzaei, Mojtaba Journal of Chemical Research, 2013 , vol. 37, # 4 p. 216 - 218

75629-49-1 ~78% 5379-88-4

文献：Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

7309-48-0 120-72-9 ~10% 5379-88-4 5379-86-2

文献：Sakai, Norio; Shimamura, Kazuyori; Ikeda, Reiko; Konakahara, Takeo Journal of Organic Chemistry, 2010 , vol. 75, # 11 p. 3923 - 3926

110-91-8 120-72-9 75-09-2 ~% 5379-88-4

文献：Matsumoto, Kiyoshi; Uchida, Takane; Hashimoto, Shiro; Yonezawa, Yukie; Iida, Hirokazu; et al. Heterocycles, 1993 , vol. 36, # 10 p. 2215 - 2220

487-89-8 ~% 5379-88-4

文献：Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721

120-72-9 5472-71-9 ~% 5379-88-4 5379-86-2

文献：Love, Brian E.; Nguyen, Binh T. Synlett, 1998 , # 10 p. 1123 - 1125

上下游产品

上游产品  9
110-91-8 700-06-1 120-72-9 50-00-0
75629-49-1 7309-48-0 75-09-2 487-89-8
5472-71-9
下游产品  0