36082-45-8

• 常用中文名：2-氨基-5-溴-4-甲氧基嘧啶
• 常用英文名：5-Bromo-4-methoxypyrimidin-2-amine
• CAS号：36082-45-8
• 分子式：C₅H₆BrN₃O
• 分子量：204.025
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 溴嘧啶
• 发布时间：2018-11-28 16:23:14
• 更新时间：2024-01-11 14:06:00

名称

• 中文名: 2-氨基-5-溴-4-甲氧基嘧啶
• 英文名: 5-bromo-4-methoxypyrimidin-2-amine
• 中文别名: 2-氨基-4-甲氧基-5-溴嘧啶
• 英文别名: 5-Brom-4-methoxy-pyrimidin-2-ylamin; 5-Bromo-4-methoxy-2-pyrimidinamine; 2-Pyrimidinamine, 5-bromo-4-methoxy-; 2-Amino-5-bromo-4-methoxypyrimidine; 5-bromo-4-methoxypyrimidin-2-amine; 5-bromo-4-methoxypyrimidine-2-ylamine; QC-867; 5-Brom-2-amino-4-methoxy-pyrimidin; 5-bromo-4-methoxypyrimidin-2-yl-amine

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 364.8±45.0 °C at 760 mmHg
• 熔点: 118ºC
• 分子式: C₅H₆BrN₃O
• 分子量: 204.025
• 闪点: 174.4±28.7 °C
• 精确质量: 202.969421
• PSA: 61.03000
• LogP: 1.40
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.610
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

155-90-8 ~98% 36082-45-8

文献：Burger, Matthew T.; Pecchi, Sabina; Wagman, Allan; Ni, Zhi-Jie; Knapp, Mark; Hendrickson, Thomas; Atallah, Gordana; Pfister, Keith; Zhang, Yanchen; Bartulis, Sarah; Frazier, Kelly; Ng, Simon; Smith, Aaron; Verhagen, Joelle; Haznedar, Joshua; Huh, Kay; Iwanowicz, Ed; Xin, Xiaohua; Menezes, Daniel; Merritt, Hanne; Lee, Isabelle; Wiesmann, Marion; Kaufman, Susan; Crawford, Kenneth; Chin, Michael; Bussiere, Dirksen; Shoemaker, Kevin; Zaror, Isabel; Maira, Sauveur-Michel; Voliva, Charles F. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 774 - 779

1044767-99-8 ~92% 36082-45-8

文献：Leahy, James W.; Buhr, Chris A.; Johnson, Henry W. B.; Kim, Byung Gyu; Baik, Taegon; Cannoy, Jonah; Forsyth, Timothy P.; Jeong, Joon Won; Lee, Matthew S.; Ma, Sunghoon; Noson, Kevin; Wang, Longcheng; Williams, Matthew; Nuss, John M.; Brooks, Eric; Foster, Paul; Goon, Leanne; Heald, Nathan; Holst, Charles; Jaeger, Christopher; Lam, Scott; Lougheed, Julie; Nguyen, Lam; Plonowski, Arthur; Song, Joanne; Stout, Thomas; Wu, Xiang; Yakes, Michael F.; Yu, Peiwen; Zhang, Wentao; Lamb, Peter; Raeber, Olivia Journal of Medicinal Chemistry, 2012 , vol. 55, # 11 p. 5467 - 5482

5734-64-5 ~% 36082-45-8

文献：ACS Medicinal Chemistry Letters, , vol. 2, # 10 p. 774 - 779

上下游产品

上游产品  3
155-90-8 1044767-99-8 5734-64-5
下游产品  2
155-90-8 944401-63-2

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%