25077-25-2

• 常用中文名：1-甲基-2,6-哌啶二酮
• 常用英文名：1-Methyl-2,6-piperidinedione
• CAS号：25077-25-2
• 分子式：C₆H₉NO₂
• 分子量：127.141
• 发布时间：2016-11-08 01:29:32
• 更新时间：2024-01-10 12:03:18

名称

• 中文名: 1-甲基-2,6-哌啶二酮
• 英文名: 1-methylpiperidine-2,6-dione
• 英文别名: N-Methylglutarimid; N-Methylglutarimide; Glutarimide,N-methyl; N-methyladipinimide; 1-Methylpiperidine-2,6-dione; 1-methyl-piperidine-2,6-dione; N-methylglutaramide; 2,6-Piperidinedione,1-methyl; 2,6-Piperidinedione, 1-methyl-; 1-Methylglutarimide; 1-Methyl-2,6-piperidinedione

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 243.8±9.0 °C at 760 mmHg
• 熔点: 30-31°C
• 分子式: C₆H₉NO₂
• 分子量: 127.141
• 闪点: 110.7±11.1 °C
• 精确质量: 127.063332
• PSA: 37.38000
• LogP: 0.35
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.484
• 储存条件: 室温，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MA5220000 CHEMICAL NAME : Glutarimide, N-methyl- CAS REGISTRY NUMBER : 25077-25-2 BEILSTEIN REFERENCE NO. : 0116172 LAST UPDATED : 199710 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C6-H9-N-O2 MOLECULAR WEIGHT : 127.16 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3400 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571226 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >512 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

安全

• 危害码 (欧洲): Xi

合成路线

931-20-4 ~92% 25077-25-2

文献：Yoshifuji, Shigeyuki; Arakawa, Yukimi; Nitta, Yoshihiro Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 1 p. 357 - 363

1121-89-7 74-88-4 ~98% 25077-25-2

文献：Marson; Khan; Porter Journal of Organic Chemistry, 2001 , vol. 66, # 14 p. 4771 - 4775

110-94-1 74-89-5 ~% 25077-25-2 56269-42-2

文献：Lukes; Smetackova Collection of Czechoslovak Chemical Communications, 1933 , vol. 5, p. 61,64 Full Text Show Details Hall et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 6420,6421

931-20-4 ~% 675-20-7 1121-89-7 25077-25-2

文献：Iley, Jim; Tolando, Roberto; Constantino, Luis Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 8 p. 1299 - 1305

186581-53-3 1121-89-7 ~% 25077-25-2

文献：Irrera Gazzetta Chimica Italiana, 1935 , vol. 65, p. 464

110-94-1 74-89-5 ~% 25077-25-2

文献：Ozawa, Naganori; Nakajima, Setsuko; Zaoya, Kyoko; Hamaguchi, Fumiko; Nagasaka, Tatsuo Heterocycles, 1991 , vol. 32, # 5 p. 889 - 894

上下游产品

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