357-66-4

• 常用中文名：螺立林
• 常用英文名：Spirilene
• CAS号：357-66-4
• 分子式：C₂₄H₂₈FN₃O
• 分子量：393.49700
• 发布时间：2018-07-09 00:21:17
• 更新时间：2025-08-21 13:20:44

名称

• 中文名: 螺立林
• 英文名: 8-[(Z)-4-(4-fluorophenyl)pent-3-enyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• 英文别名: Espirileno [INN-Spanish]; 1,3,8-Triazaspiro(4,5)decan-4-one,8-(4-(fluorophenyl)-3-pentenyl)-1-phenyl; Espirileno; 8-[4-(4-fluoro-phenyl)-pent-3-enyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one; Spirilene; R 6109; Isospirilene; Spirilenum [INN-Latin]; 8-(4-(p-Fluorophenyl)-3-pentenyl)-1-phenyl-1,3,8-triazaspiro(4,5)decan-4-one; 1,3,8-Triazaspiro(4.5)decan-4-one,8-(4-(p-fluorophenyl)-3-penenyl)-1-phenyl

物化性质

• 密度: 1.21g/cm3
• 沸点: 607ºC at 760mmHg
• 分子式: C₂₄H₂₈FN₃O
• 分子量: 393.49700
• 闪点: 320.9ºC
• 精确质量: 393.22200
• PSA: 35.58000
• LogP: 4.37930
• 折射率: 1.623

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XX9275000 CHEMICAL NAME : 1,3,8-Triazaspiro(4,5)decan-4-one, 8-(4-(fluorophenyl)-3-pentenyl)-1-phenyl- CAS REGISTRY NUMBER : 357-66-4 BEILSTEIN REFERENCE NO. : 0632225 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C24-H28-F-N3-O MOLECULAR WEIGHT : 393.55 WISWESSER LINE NOTATION : T6N DXTJ A3UY1&R DF& D-& CT5MVXN EHJ DR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,304,1972