75464-11-8

• 常用中文名：布蒽酮
• 常用英文名：Butantrone
• CAS号：75464-11-8
• 分子式：C₁₈H₁₆O₄
• 分子量：296.31700
• 发布时间：2018-06-05 08:00:00
• 更新时间：2025-08-25 16:55:17

名称

• 中文名: 布蒽酮
• 英文名: 10-butanoyl-1,8-dihydroxy-10H-anthracen-9-one
• 英文别名: 10-butyryl-1,8-dihydroxy-9-anthron; Butantrona [Spanish]; Butantronum [Latin]; Dithranol,10-butyryl; 1,8-dihydroxy-10-(1'-oxobutyl)-9(10H)-anthracenone; 9(10H)-ANTHRACENONE,1,8-DIHYDROXY-10-(1-OXOBUTYL); Butantrona; 1,8-dihydroxy-10-butyrylanthrone; 10-Butyryl dithranol; 10-butyryl-1,8-dihydroxy-9(10H)-anthracenone; Butantrone

物化性质

• 密度: 1.324g/cm3
• 沸点: 490.1ºC at 760 mmHg
• 分子式: C₁₈H₁₆O₄
• 分子量: 296.31700
• 闪点: 264.3ºC
• 精确质量: 296.10500
• PSA: 74.60000
• LogP: 3.14330
• 折射率: 1.641

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CB1500000 CHEMICAL NAME : 9(10H)-Anthracenone, 1,8-dihydroxy-10-(1-oxobutyl)- CAS REGISTRY NUMBER : 75464-11-8 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C18-H16-O4 MOLECULAR WEIGHT : 296.34 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1579 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 139 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,180,1986

合成路线

1143-38-0 141-75-3 ~% 75464-11-8

文献：Groupement d'Interet Economique dit: Centre International 'de Recherches Dermatologiques C.I.R.D. Patent: US4696941 A1, 1987 ;

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