500-55-0

• 常用中文名：阿朴阿托品
• 常用英文名：8-Methyl-8-azabicyclo[3.2.1]oct-3-yl atropate
• CAS号：500-55-0
• 分子式：C₁₇H₂₁NO₂
• 分子量：271.354
• 发布时间：2018-09-14 09:33:01
• 更新时间：2025-08-27 18:51:46

名称

• 中文名: 阿朴阿托品
• 英文名: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-phenylprop-2-enoate
• 中文别名: 變顛茄鹼
• 英文别名: Apohyoscyamine; atropic acid tropane-3endo-yl ester; Atropamin; Apoatropin; Atropasaeure-tropan-3endo-ylester; Atropyltropeine; Benzeneacetic acid, α-methylene-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Propenoic acid, 2-phenyl-, 8-methyl-8-azabicyclo[3.2.1]octan-3-yl ester; 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl atropate; Apohyoscyamin; Benzeneacetic acid, α-methylene-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-; Tropine,atropate (ester); Apoatropine; Atropamine

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 389.1±42.0 °C at 760 mmHg
• 分子式: C₁₇H₂₁NO₂
• 分子量: 271.354
• 闪点: 136.5±18.8 °C
• 精确质量: 271.157227
• PSA: 29.54000
• LogP: 3.22
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.572
• 储存条件: 库房通风低温干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YM4025000 CHEMICAL NAME : 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, atropate (ester) CAS REGISTRY NUMBER : 500-55-0 BEILSTEIN REFERENCE NO. : 0085429 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H21-N-O2 MOLECULAR WEIGHT : 271.39 WISWESSER LINE NOTATION : T56 A ANTJ A1 GOVYR&U1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 160 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,117,1989 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10400 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-203644

安全

• 风险声明 (欧洲): 26/28
• 危险品运输编码: UN 1544
• 海关编码: 2933990090

合成路线

上下游产品

上游产品  10
51-55-8 101-31-5 7697-37-2 108-24-7
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下游产品  4
492-38-6 7432-10-2 2292-12-8 2292-11-7

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%