4564-87-8

• 常用中文名：卡波霉素
• 常用英文名：Leucomycin V,9-deoxy-12,13-epoxy-12,13-dihydro-9-oxo-, 3-acetate 4B-(3-methylbutanoate),(12S,13S)-
• CAS号：4564-87-8
• 分子式：C₄₂H₆₇NO₁₆
• 分子量：841.97800
• 发布时间：2018-09-22 13:24:17
• 更新时间：2024-01-11 14:55:02

名称

• 中文名: 卡波霉素
• 英文名: 10-Hexadecenoic acid, 5-[[4-(diemthylamino)tetrahydro-3-hydroxy-6-methyl-5-[(tetrahydro-4,5-dihydroxy-4,6-dimethylpyran-2-yl)oxy]-pyran-2-yl]oxy]-12,13-epoxy-6-(formylmethyl)-3,15-dihydroxy-4-methoxy-8-methyl-9-oxo-,.ω.-lactone, acetate, isovalerate
• 英文别名: DeltaMycin A4; M 4209; Magnamycin-A; MagnaMycin; carbomycin; CarboMycin A

物化性质

• 密度: 1.24g/cm3
• 沸点: 892.2ºC at 760mmHg
• 熔点: 214ºC
• 分子式: C₄₂H₆₇NO₁₆
• 分子量: 841.97800
• 闪点: 493.4ºC
• 精确质量: 841.44600
• PSA: 215.42000
• LogP: 2.43280
• 折射率: 1.535
• 储存条件: 库房低温通风干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OH4727000 CHEMICAL NAME : Leucomycin V, 9-deoxy-12,13-epoxy-12,13-dihydro-9-oxo-, 3-acetate 4B-(3-methylbutanoate), (12S,13S)- CAS REGISTRY NUMBER : 4564-87-8 LAST UPDATED : 199706 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C42-H67-N-O16 MOLECULAR WEIGHT : 842.10 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,336,1954/1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2950 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 3,117,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 550 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 3,117,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 3,117,1953