13877-76-4

• 常用中文名：间型霉素B
• 常用英文名：7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl-
• CAS号：13877-76-4
• 分子式：C₁₀H₁₂N₄O₅
• 分子量：268.22600
• 发布时间：2018-05-31 08:00:00
• 更新时间：2024-01-09 18:11:30

名称

• 中文名: 间型霉素B
• 英文名: formycin B
• 英文别名: FORMYCIN B; LAURUSIN; D-Ribitol, 1,4-anhydro-1-C-(6,7-dihydro-7-oxo-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-, (S)-; OHYAMYCIN

物化性质

• 密度: 2.18g/cm3
• 沸点: 683.2ºC at 760mmHg
• 分子式: C₁₀H₁₂N₄O₅
• 分子量: 268.22600
• 闪点: 367ºC
• 精确质量: 268.08100
• PSA: 144.35000
• 蒸汽压: 1.34E-19mmHg at 25°C
• 折射率: 1.921

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR0800000 CHEMICAL NAME : 7H-Pyrazolo(4,3-d)pyrimidin-7-one, 1,4-dihydro-3-beta-D-ribofuranosyl- CAS REGISTRY NUMBER : 13877-76-4 LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C10-H12-N4-O5 MOLECULAR WEIGHT : 268.26 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg/10D-I TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 10 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 30,2651,1981

合成路线

107-31-3 62160-01-4 ~69% 13877-76-4

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

75156-05-7 ~% 13877-76-4

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

94827-25-5 ~% 13877-76-4

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

94827-23-3 ~% 13877-76-4

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

94827-24-4 ~% 13877-76-4

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2367 - 2371

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