511-09-1

• 常用中文名：麦角克碱
• 常用英文名：alpha-ergocryptine
• CAS号：511-09-1
• 分子式：C₃₂H₄₁N₅O₅
• 分子量：575.698
• 发布时间：2018-02-09 08:00:00
• 更新时间：2024-01-11 16:09:38

名称

• 中文名: 麦角克碱
• 英文名: α-ergocryptine
• 中文别名: 麦角脊亭; alpha-麦角隐亭
• 英文别名: (5'a)-12'-Hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione; Ergocryptine; 12'-hydroxy-5'; Ergotaman, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxo-, (5'α)-; alpha-ergocryptine; (5'α)-12'-Hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman; α-Ergocryptine; a-Ergocryptine; 12'-Hydroxy-5'α-isobutyl-2'-isopropylergotaman-3',6',18-trione; Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'α)-; Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'α,10α)-; 12'-Hydroxy-2'-(1-methylethyl)-5'-α-(2-methylpropyl)ergotaman-3',6',18-trione; (6aR,9R)-N-[(2R,5S,10aS,10bS)-10b-Hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide; (5'α)-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman; Ergotaman-3',6',18-trione, 12'-hydroxy-2'- (1-methylethyl)-5'-(2-methylpropyl)-, (5'α)-; 4-25-00-00964

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 861.7±65.0 °C at 760 mmHg
• 熔点: 152-154ºC
• 分子式: C₃₂H₄₁N₅O₅
• 分子量: 575.698
• 闪点: 475.0±34.3 °C
• 精确质量: 575.310791
• PSA: 118.21000
• LogP: 4.08
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.681

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KE1400000 CHEMICAL NAME : Ergocryptine CAS REGISTRY NUMBER : 511-09-1 BEILSTEIN REFERENCE NO. : 0078810 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C32-H41-N5-O5 MOLECULAR WEIGHT : 575.78 WISWESSER LINE NOTATION : T C6656 1A P GN LM CUTT&&J G1 EVM- DT B565 CO EVN HVNTJ BQ DY1&1 G1Y1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 950 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3752814 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2 mg/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 56,691,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 1800 ug/kg SEX/DURATION : lactating female 3 day(s) post-birth TOXIC EFFECTS : Reproductive - Maternal Effects - postpartum REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3752814

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 62
• 危险品运输编码: UN 1544 6.1/PG 3
• WGK德国: 3
• 包装等级: III
• 危险类别: 6.1(b)

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