16154-72-6

• 常用中文名：1-(4-氨基-2-氯苯基)-4-甲基哌嗪
• 常用英文名：3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine
• CAS号：16154-72-6
• 分子式：C₁₁H₁₆ClN₃
• 分子量：225.718
• 发布时间：2018-12-12 17:34:53
• 更新时间：2025-08-25 10:04:08

名称

• 中文名: 1-(4-氨基-2-氯苯基)-4-甲基哌嗪
• 英文名: 3-chloro-4-(4-methylpiperazin-1-yl)aniline
• 中文别名: 1-(4-氨基-2-氯苯)-4-甲基哌嗪
• 英文别名: 3-chloro-4-(4-methyl-piperazin-1-yl)-aniline; [3-chloro-4-(4-methyl-1-piperazinyl)phenyl]amine; benzenamine,3-chloro-4-(4-methyl-1-piperazinyl); 3-chloro-4-(4-methylpiperazinyl)phenylamine; 4-(3-chloro-4-methylpiperazin-1-yl)aniline; 3-Chloro-4-(4-methyl-1-piperazinyl)aniline; 1-(4-Amino-2-Chlorophenyl)-4-methylpiperazine; 3-Chloro-4-(4-methyl-piperazin-1-yl)-phenylamine; Benzenamine, 3-chloro-4-(4-methyl-1-piperazinyl)-; 3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 382.1±42.0 °C at 760 mmHg
• 分子式: C₁₁H₁₆ClN₃
• 分子量: 225.718
• 闪点: 184.9±27.9 °C
• 精确质量: 225.103271
• PSA: 32.50000
• LogP: 1.76
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.599
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2933599090

合成路线

16154-62-4 ~97% 16154-72-6

文献：GLAXO GROUP LIMITED; CASILLAS, Linda, N.; CHAKRAVORTY, Subhas, J.; EIDAM, Patrick; HAILE, Pamela, A.; HUGHES, Terry, Vincent; LAKDAWALA SHAH, Ami; LEISTER, Lara, Kathryn; MILLER, Nathan, Andrew; RAHMAN, Attiq; SEHON, Clark, A.; WANG, Gren, Z.; ZHANG, Daohua Patent: WO2011/120026 A1, 2011 ; Location in patent: Page/Page column 35 ; WO 2011/120026 A1

915020-32-5 ~% 16154-72-6

文献：WO2006/122806 A2, ; Page/Page column 66 ; WO 2006/122806 A2

109-01-3 350-30-1 ~% 16154-72-6

文献：WO2011/120026 A1, ; WO 2011/120026 A1

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%