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2205-73-4

2205-73-4结构式

常用中文名：硫甲睾酮
常用英文名：S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-acetylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate
CAS号：2205-73-4
分子式：C₂₄H₃₄O₄S₂
分子量：450.65400
发布时间：2018-08-27 17:15:55
更新时间：2024-04-03 01:00:48

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中文名	硫甲睾酮
英文名	S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-acetylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate
英文别名	STA-307 Thiomestrone Emdabol Emdabolin Embadol Tiomesterona [INN-Spanish] Protabol Tiomesteronum [INN-Latin] Tiomesterone Thiomesterone

密度	1.25g/cm3
沸点	588.1ºC at 760mmHg
分子式	C₂₄H₃₄O₄S₂
分子量	450.65400
闪点	309.5ºC
精确质量	450.19000
PSA	122.04000
LogP	4.78570
蒸汽压	2.79E-16mmHg at 25°C
折射率	1.595

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BV8396900

CHEMICAL NAME :: Androst-4-en-3-one, 17-beta-hydroxy-1-alpha,7-alpha-dimercapto-17-methyl- , 1,7-diacetate

CAS REGISTRY NUMBER :: 2205-73-4

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C24-H34-O4-S2

MOLECULAR WEIGHT :: 450.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: male 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: female 10 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964