55556-93-9

• 常用中文名：N-nitroso-4-hydroxypiperidine
• 常用英文名：N-nitroso-4-hydroxypiperidine
• CAS号：55556-93-9
• 分子式：C₅H₁₀N₂O₂
• 分子量：130.14500
• 发布时间：2016-09-25 04:02:21
• 更新时间：2024-01-14 20:24:55

名称

• 英文名: 1-nitrosopiperidin-4-ol
• 英文别名: N-Nitroso-4-piperidinol; Nitroso-4-piperidinol; 4-PIPERIDINOL,N-NITROSO; N-Nitroso-4-hydroxypiperidine; 4-hydroxy-N-nitrosopiperidine; 1-nitroso-piperidin-4-ol; 4-Piperidinol,1-nitroso; Nitrosopiperidinol

物化性质

• 密度: 1.37g/cm3
• 沸点: 309.3ºC at 760 mmHg
• 分子式: C₅H₁₀N₂O₂
• 分子量: 130.14500
• 闪点: 140.8ºC
• 精确质量: 130.07400
• PSA: 52.90000
• LogP: 0.06240
• 折射率: 1.588

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TN7848000 CHEMICAL NAME : 4-Piperidinol, N-nitroso- CAS REGISTRY NUMBER : 55556-93-9 BEILSTEIN REFERENCE NO. : 1447942 LAST UPDATED : 199612 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C5-H10-N2-O2 MOLECULAR WEIGHT : 130.17 WISWESSER LINE NOTATION : T6NTJ ANO DQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1666 mg/kg/36W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Liver - tumors MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 400 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 56,131,1977

合成路线

5382-16-1 ~97% 55556-93-9

文献：ELI LILLY AND COMPANY Patent: WO2007/127688 A2, 2007 ; Location in patent: Page/Page column 38; 47 ;

100-75-4 ~1% 55556-93-9

文献：Smith, John R. Lindsay; Nee, Michael W.; Noar, J. Barry; Bruice, Thomas C. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 2 p. 255 - 260

100-75-4 ~% 55556-91-7 55556-93-9 55556-85-9

文献：Smith, John R. Lindsay; Nee, Michael W.; Noar, J. Barry; Bruice, Thomas C. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 2 p. 255 - 260

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