850452-53-8

• 常用中文名：tert-butyl 4-acetyloxypiperidine-1-carboxylate
• 常用英文名：tert-butyl 4-acetyloxypiperidine-1-carboxylate
• CAS号：850452-53-8
• 分子式：C₁₂H₂₁NO₄
• 分子量：243.29900
• 发布时间：2016-11-04 12:13:09
• 更新时间：2024-01-09 10:46:11

名称

• 英文名: tert-butyl 4-acetyloxypiperidine-1-carboxylate
• 英文别名: 2-methylpropan-2-yl 4-(acetyloxy)piperidine-1-carboxylate; N-tert-butoxycarbonylpiperidin-4-yl acetate; 1-Piperidinecarboxylic acid,4-(acetyloxy)-,1,1-dimethylethyl ester; 1,1-dimethylethyl 4-(acetyloxy)-1-piperidinecarboxylate

物化性质

• 分子式: C₁₂H₂₁NO₄
• 分子量: 243.29900
• 精确质量: 243.14700
• PSA: 55.84000
• LogP: 1.88690

合成路线

108-24-7 109384-19-2 ~99% 850452-53-8

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2008/8895 A1, 2008 ; Location in patent: Page/Page column 163 ; WO 2008/008895 A1

75-36-5 109384-19-2 ~81% 850452-53-8

文献：Kikuchi, Tatsuya; Zhang, Ming-Rong; Ikota, Nobuo; Fukushi, Kiyoshi; Okamura, Toshimitsu; Suzuki, Kazutoshi; Arano, Yasushi; Irie, Toshiaki Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2577 - 2583

24424-99-5 ~% 850452-53-8

文献：Zhang, Ming-Rong; Furutsuka, Kenji; Maeda, Jun; Kikuchi, Tatsuya; Kida, Takayo; Okauchi, Takashi; Irie, Toshiaki; Suzuki, Kazutoshi Bioorganic and medicinal chemistry, 2003 , vol. 11, # 12 p. 2519 - 2527

5382-17-2 ~% 850452-53-8

文献：Zhang, Ming-Rong; Furutsuka, Kenji; Maeda, Jun; Kikuchi, Tatsuya; Kida, Takayo; Okauchi, Takashi; Irie, Toshiaki; Suzuki, Kazutoshi Bioorganic and medicinal chemistry, 2003 , vol. 11, # 12 p. 2519 - 2527

5382-16-1 ~% 850452-53-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stephanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: US2013/261106 A1, 2013 ;

5382-16-1 24424-99-5 ~% 850452-53-8

文献：SANOFI; CARRY, Jean-Christophe; CHATREAUX, Fabienne; DEPRETS, Stéphanie; DUCLOS, Olivier; LEROY, Vincent; MALLART, Sergio; MELON-MANGUER, Dominique; MENDEZ-PEREZ, Maria; VERGNE, Fabrice Patent: WO2013/150036 A1, 2013 ;