161373-48-4

• 常用中文名：4-amino-6,7-dichlorocinnoline-3-carboxylic acid
• 常用英文名：4-amino-6,7-dichlorocinnoline-3-carboxylic acid
• CAS号：161373-48-4
• 分子式：C₉H₅Cl₂N₃O₂
• 分子量：258.06100
• 发布时间：2016-11-03 13:30:51
• 更新时间：2024-01-31 17:45:25

名称

• 英文名: 4-amino-6,7-dichlorocinnoline-3-carboxylic acid
• 英文别名: 4-Amino-6,7-dichloro-3-cinnolinecarboxylic acid hydrate; 3-Cinnolinecarboxylic acid,4-amino-6,7-dichloro-,hydrate

物化性质

• 密度: 1.735g/cm3
• 沸点: 489.3ºC at 760 mmHg
• 分子式: C₉H₅Cl₂N₃O₂
• 分子量: 258.06100
• 闪点: 249.7ºC
• 精确质量: 256.97600
• PSA: 89.10000
• LogP: 2.79820
• 蒸汽压: 2.17E-10mmHg at 25°C
• 折射率: 1.76

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GE3624734 CHEMICAL NAME : 3-Cinnolinecarboxylic acid, 4-amino-6,7-dichloro-, hydrate CAS REGISTRY NUMBER : 161373-48-4 LAST UPDATED : 199603 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H5-Cl2-N3-O2.H2-O MOLECULAR WEIGHT : 276.09 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994

合成路线

161373-35-9 ~83% 161373-48-4

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

95-76-1 ~% 161373-48-4

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

59064-01-6 ~% 161373-48-4

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889