474-45-3

• 常用中文名：丝胶树碱
• 常用英文名：3alpha-amino-5alpha-pregnan-20-one
• CAS号：474-45-3
• 分子式：C₂₁H₃₅NO
• 分子量：317.50900
• 发布时间：2018-05-26 08:00:00
• 更新时间：2025-08-25 09:39:38

名称

• 中文名: 丝胶树碱
• 英文名: (3α,5α)-3-Aminopregnan-20-one
• 英文别名: Amafolona [INN-Spanish]; (2beta,3alpha,5alpha)-3-Amino-2-hydroxyandrostan-17-one,hydrochloride; Amafolonum; Amafolona; Amafolone; Amafolonum [INN-Latin]

物化性质

• 密度: 1.014g/cm3
• 沸点: 419.9ºC at 760mmHg
• 分子式: C₂₁H₃₅NO
• 分子量: 317.50900
• 闪点: 207.8ºC
• 精确质量: 317.27200
• PSA: 43.09000
• LogP: 5.26190
• 蒸汽压: 2.93E-07mmHg at 25°C
• 折射率: 1.516
• 储存条件: -20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU4375000 CHEMICAL NAME : 5-alpha-Pregnan-20-one, 3-alpha-amino- CAS REGISTRY NUMBER : 474-45-3 LAST UPDATED : 199709 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H35-N-O MOLECULAR WEIGHT : 317.57 WISWESSER LINE NOTATION : L E5 B666TJ A1 E1 FV1 OZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CHDDAT Comptes Rendus des Seances de l'Academie des Sciences, Serie D: Sciences Naturelles. (Paris, France) V.262-291, 1966-80. For publisher information, see CRASEV. Volume(issue)/page/year: 274,2830,1972 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 64 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 18,177,1960

安全

• 危害码 (欧洲): Xn