1185516-79-3

• 常用中文名：(S)-2-(2,6,7,8-四氢-1H-茚并[5,4-B]呋喃-8-基)乙腈
• 常用英文名：(S)-2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetonitrile
• CAS号：1185516-79-3
• 分子式：C₁₃H₁₃NO
• 分子量：199.24800
• 发布时间：2017-02-06 19:32:06
• 更新时间：2024-01-09 06:54:04

名称

• 中文名: (S)-2-(2,6,7,8-四氢-1H-茚并[5,4-B]呋喃-8-基)乙腈
• 英文名: (8S)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylacetonitrile
• 英文别名: (8'rC2,8'at,11'at,11'bt)-11'a,11'b-dihydro-8'aH-spiro[furan-3,8'-furo[3',4':3,4]pyrrolo[2,1-a]phthalazine]-2,5,9',11'-tetraone; (1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)acetonitrile; (S)-2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetonitrile; 11a',11b'-Dihydro-11'H-spiro[furan-3,8'-furo[3',4':3,4]pyrrolo[2,1-a]phthalazine]-2,5,9',11'(4H,8a'H)-tetrone; (S)-2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetonitrile; Ramelteon Impurity 12

物化性质

• 分子式: C₁₃H₁₃NO
• 分子量: 199.24800
• 精确质量: 199.10000
• PSA: 33.02000
• LogP: 2.56498

合成路线

221530-38-7 ~70% 1185516-79-3

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.; KANSAL, Vinod, Kumar; MISTRY, Dhirenkumar, N.; VASOYA, Sanjay, L.; JADAV, Arpan, M.; DADHANIYA, Pratish; NALAWADE, Jitendra Patent: WO2010/45565 A1, 2010 ; Location in patent: Page/Page column 42 ;

196597-79-2 ~% 1185516-79-3 1221160-66-2

文献：LEK PHARMACEUTICALS D.D.; CLUZEAU, Jerome Patent: WO2010/92107 A1, 2010 ; Location in patent: Page/Page column 23 ;

1242672-40-7 ~% 1185516-79-3

文献：Lenna, Roberto; Ghidoli, Cristina; Panza, Luigi Patent: US2010/234622 A1, 2010 ; Location in patent: Page/Page column 10-11 ;

221530-44-5 ~% 1185516-79-3

文献：MEDICHEM, S.A. Patent: WO2009/106966 A1, 2009 ; Location in patent: Page/Page column 7-8 ;

1217272-33-7 ~% 1185516-79-3 1221160-66-2

文献：USV LIMITED; SATHE, Dhananjay, Govind; BHISE, Nandu, Baban; GATNE, Parag, Sukumar; PATNEKAR, Subodh, Shashikant; DEORE, Raviraj, Bhatu; MAHAJAN, Anil, Dinkar Patent: WO2010/41271 A2, 2010 ; Location in patent: Page/Page column 32 ;

上下游产品

上游产品  5
221530-38-7 196597-79-2 1242672-40-7 221530-44-5
1217272-33-7
下游产品  1
196597-26-9