101376-26-5

• 常用中文名：(R)-(4-苄基-3-吗啡啉)-甲醇
• 常用英文名：(4-Benzyl-3-morpholinyl)methanol
• CAS号：101376-26-5
• 分子式：C₁₂H₁₇NO₂
• 分子量：207.269
• 发布时间：2018-12-24 10:54:02
• 更新时间：2024-01-08 12:10:10

名称

• 中文名: (R)-(4-苄基-3-吗啡啉)-甲醇
• 英文名: (R)-(4-Benzylmorpholin-3-yl)methanol
• 中文别名: (R)-4-苄基-3-羟基甲基吗啉
• 英文别名: 3-Morpholinemethanol, 4-(phenylmethyl)-, (3R)-; (4-Benzyl-3-morpholinyl)methanol; (4-benzylmorpholin-3-yl)methanol; [(3R)-4-Benzyl-3-morpholinyl]methanol; 3-Morpholinemethanol, 4-(phenylmethyl)-; [(3R)-4-Benzylmorpholin-3-yl]methanol

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 322.7±22.0 °C at 760 mmHg
• 分子式: C₁₂H₁₇NO₂
• 分子量: 207.269
• 闪点: 149.0±22.3 °C
• 精确质量: 207.125931
• PSA: 32.70000
• LogP: 1.28
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.549
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

106973-37-9 ~86% 101376-26-5

文献：Dainippon Sumitomo Pharma Co., Ltd.; MARUYAMA, Megumi; KINOMURA, Naoya; NOJIMA, Satoshi; TAKAMURA, Masahiro; KAKIGUCHI, Keisuke; TATAMITANI, Hiroto Patent: WO2011/111875 A1, 2011 ; Location in patent: Page/Page column 90-91 ; WO 2011/111875 A1

211053-49-5 100-39-0 ~89% 101376-26-5

文献：MEDIVIR AB; AYESA, Susana; BELDA, Oscar; BJÖRKLUND, Catarina; NILSSON, Magnus; RUSSO, Francesco; SAHLBERG, Christer; WIKTELIUS, Daniel Patent: WO2013/95275 A1, 2013 ; Location in patent: Page/Page column 48; 49 ;

106910-76-3 ~% 101376-26-5

文献：Dainippon Sumitomo Pharma Co., Ltd.; MARUYAMA, Megumi; KINOMURA, Naoya; NOJIMA, Satoshi; TAKAMURA, Masahiro; KAKIGUCHI, Keisuke; TATAMITANI, Hiroto Patent: WO2011/111875 A1, 2011 ; WO 2011/111875 A1

714971-27-4 ~% 101376-26-5

文献：Gavai, Ashvinikumar V.; Fink, Brian E.; Fairfax, David J.; Martin, Gregory S.; Rossiter, Lana M.; Holst, Christian L.; Kim, Soong-Hoon; Leavitt, Kenneth J.; Mastalerz, Harold; Han, Wen-Ching; Norris, Derek; Goyal, Bindu; Swaminathan, Shankar; Patel, Bharat; Mathur, Arvind; Vyas, Dolatrai M.; Tokarski, John S.; Chiang, Yu; Oppenheimer, Simone; Hongjian, Zhang; Marathe, Punit; Fargnoli, Joseph; Lee, Francis Y.; Wong, Tai W.; Vite, Gregory D. Journal of Medicinal Chemistry, 2009 , vol. 52, # 21 p. 6527 - 6530

100-52-7 ~% 101376-26-5

文献：Brown, George R.; Foubister, Alan J.; Wright, Brian Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2577 - 2580

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