5586-87-8

• 常用中文名：N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐
• 常用英文名：N-(3-chloropropyl)-1-phenylpropan-2-amine,hydrochloride
• CAS号：5586-87-8
• 分子式：C₁₂H₁₉Cl₂N
• 分子量：248.19200
• 发布时间：2018-12-17 11:59:01
• 更新时间：2024-01-03 15:51:17

名称

• 中文名: N-(3-氯丙基)-alpha-甲基苯乙胺盐酸盐
• 英文名: N-(3-chloropropyl)-1-phenylpropan-2-amine,hydrochloride
• 英文别名: Mefenorex HCl; Doracil; Pondinil; EINECS 226-985-9; Rondimen; Ro 4-5282; N-Chloropropylamphetamine hydrochloride; R 4-5282; Mefenorex hydrochloride

物化性质

• 沸点: 305.1ºC at 760mmHg
• 分子式: C₁₂H₁₉Cl₂N
• 分子量: 248.19200
• 闪点: 138.3ºC
• 精确质量: 247.08900
• PSA: 12.03000
• LogP: 4.02900

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SH2100000 CHEMICAL NAME : Phenethylamine, N-(3-chloropropyl)-alpha-methyl-, hydrochloride CAS REGISTRY NUMBER : 5586-87-8 LAST UPDATED : 199512 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C12-H18-Cl-N.Cl-H MOLECULAR WEIGHT : 248.22 WISWESSER LINE NOTATION : G3MY1&1R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 410 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 230 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 144 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,748,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 49 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 236 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,356,1972