CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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NL5075000
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CHEMICAL NAME :
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Indole, 1-benzyl-3-(2-(4-pyridyl)ethyl)-, monohydrochloride
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CAS REGISTRY NUMBER :
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5585-71-7
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LAST UPDATED :
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199009
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C22-H20-N2.Cl-H
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MOLECULAR WEIGHT :
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348.90
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WISWESSER LINE NOTATION :
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T56 BNJ B1R& D2- DT6NJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human
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DOSE/DURATION :
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714 ug/kg/D
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TOXIC EFFECTS :
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Behavioral - antianxiety Vascular - BP elevation not characterized in autonomic section
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REFERENCE :
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AMCTAH Antibiotic Medicine and Clinical Therapy (New York). (New York, NY) V.3-8, 1956-61. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,521,1959
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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520 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 125,122,1959
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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98 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 125,122,1959
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