15387-10-7

• 常用中文名：烟丙法宗
• 常用英文名：N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide
• CAS号：15387-10-7
• 分子式：C₂₁H₂₅N₅O₂
• 分子量：379.45600
• 发布时间：2018-06-20 11:28:29
• 更新时间：2024-01-10 15:11:21

名称

• 中文名: 烟丙法宗
• 英文名: N-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-propan-2-ylamino]methyl]pyridine-3-carboxamide
• 英文别名: Ra 101 (pharmaceutical); Niprofazonum [INN-Latin]; 1-Phenyl-2,3-dimethyl-4(N-nicotinamidomethyl-N-isopropyl)amino-5-pyrazolone; Nicotinamide,N-((antipyrinylisopropylamino)methyl); Nicotinamidomethylaminopyrazolone; Niprofazona [INN-Spanish]; Niprofazone; RA 101; N-{[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-isopropyl-amino]-methyl}-nicotinamide; N-((Antipyrinylisopropylamino)methyl)nicotinamide

物化性质

• 密度: 1.25g/cm3
• 分子式: C₂₁H₂₅N₅O₂
• 分子量: 379.45600
• 精确质量: 379.20100
• PSA: 72.16000
• LogP: 2.87260
• 折射率: 1.638
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QS4025000 CHEMICAL NAME : Nicotinamide, N-((antipyrinylisopropylamino)methyl)- CAS REGISTRY NUMBER : 15387-10-7 BEILSTEIN REFERENCE NO. : 0766712 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C21-H25-N5-O2 MOLECULAR WEIGHT : 379.51 WISWESSER LINE NOTATION : T6NJ CVM1NY1&1&- DT5NNVJ A1 BR& E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1460 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1060 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 853 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970