105102-20-3

• 常用中文名：利罗定
• 常用英文名：Liroldine
• CAS号：105102-20-3
• 分子式：C₂₀H₂₀F₂N₄
• 分子量：354.39600
• 发布时间：2018-07-14 17:30:06
• 更新时间：2025-08-25 19:58:56

名称

• 中文名: 利罗定
• 英文名: N-[4-[4-(3,4-dihydro-2H-pyrrol-5-ylamino)-3-fluorophenyl]-2-fluorophenyl]-3,4-dihydro-2H-pyrrol-5-amine
• 英文别名: Liroldina [Spanish]; HL 707; 2,2'-((3,3'-Difluoro-4,4'-biphenylylene)dinitrilo)dipyrolidine; Liroldine [INN]; (1,1'-Biphenyl)-4,4'-diamine,N,N'-bis(3,4-dihydro-2H-pyrrol-5-yl)-3,3'-difluoro; Liroldinum [Latin]; Liroldinum; Liroldina; Liroldine; N,N'-Bis(3,4-dihydro-2H-pyrrol-5-yl)-3,3'-difluoro-(1,1'-biphenyl)-4,4'-diamine

物化性质

• 密度: 1.33g/cm3
• 沸点: 549.2ºC at 760 mmHg
• 分子式: C₂₀H₂₀F₂N₄
• 分子量: 354.39600
• 闪点: 285.9ºC
• 精确质量: 354.16600
• PSA: 48.78000
• LogP: 5.11620
• 蒸汽压: 4.13E-12mmHg at 25°C
• 折射率: 1.648

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DV2205000 CHEMICAL NAME : (1,1'-Biphenyl)-4,4'-diamine, N,N'-bis(3,4-dihydro-2H-pyrrol-5-yl)-3,3'-difluoro- CAS REGISTRY NUMBER : 105102-20-3 LAST UPDATED : 199806 DATA ITEMS CITED : 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 910 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 35,765,1997 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 940 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 35,765,1997