3688-85-5

• 常用中文名：硫米齐特
• 常用英文名：4-CHLORO-N-METHYL-3-(METHYLSULFAMO-YL)BENZAMIDE
• CAS号：3688-85-5
• 分子式：C₉H₁₁ClN₂O₃S
• 分子量：262.71300
• 发布时间：2018-07-01 01:04:11
• 更新时间：2024-03-01 23:06:12

名称

• 中文名: 硫米齐特
• 英文名: 4-chloro-N-methyl-3-(methylsulfamoyl)benzamide
• 英文别名: 4-Chlor-N-methyl-3-(methylsulfamoyl)-benzamid; Tiamizide; Diapamide [USAN]; Vectren; Thiamizide; CI-456; Tiamizid; Tiamizida [INN-Spanish]; Tiamizidum [INN-Latin]; Diapamide

物化性质

• 密度: 1.365g/cm3
• 分子式: C₉H₁₁ClN₂O₃S
• 分子量: 262.71300
• 精确质量: 262.01800
• PSA: 83.65000
• LogP: 2.47030
• 折射率: 1.554
• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.8

  2.氢键供体数量:2

  3.氢键受体数量:4

  4.可旋转化学键数量:3

  5.互变异构体数量:2

  6.拓扑分子极性表面积:83.6

  7.重原子数量:16

  8.表面电荷:0

  9.复杂度:352

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CV2451800 CHEMICAL NAME : Benzamide, 4-chloro-N-methyl-3-(methylsulfamoyl)- CAS REGISTRY NUMBER : 3688-85-5 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C9-H11-Cl-N2-O3-S MOLECULAR WEIGHT : 262.73 WISWESSER LINE NOTATION : 1MVR DG CSWM1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2580 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 520 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JNDRAK Journal of New Drugs. (Albany, NY) V.1-6, 1961-66. For publisher information, see JCPCBR. Volume(issue)/page/year: 3,302,1963

安全

• 海关编码: 2935009090

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%