105706-75-0

• 常用中文名：1-N-苄氧羰基-2-羟甲基哌啶
• 常用英文名：N- CBZ-2-piperidinemethanol
• CAS号：105706-75-0
• 分子式：C₁₄H₁₉NO₃
• 分子量：249.306
• 发布时间：2018-12-25 20:35:25
• 更新时间：2025-08-25 18:09:40

名称

• 中文名: 1-N-苄氧羰基-2-羟甲基哌啶
• 英文名: 1-cbz-2-hydroxymethyl-piperidine
• 中文别名: 1-N-Cbz-哌啶-2-甲醇; 1-Cbz-2-羟基甲基哌啶
• 英文别名: 2-Hydroxymethyl-piperidine-1-carboxylic acid benzyl ester; 1-Benzyloxycarbonyl-2-piperidinemethanol; 1-Piperidinecarboxylic acid, 2-(hydroxymethyl)-, phenylmethyl ester; N-benzyloxycarbonyl-2-hydroxymethylpiperidine; Benzyl 2-(hydroxymethyl)piperidine-1-carboxylate; Benzyl 2-(hydroxymethyl) piperidine-1-Carboxylate; 1-Cbz-2-piperidinemethanol; Benzyl 2-(hydroxymethyl)-1-piperidinecarboxylate; N-Benzyloxycarbonyl-2-piperidineMethanol; 1-benzyloxycarbonyl-2-hydroxymethylpiperidine; N- CBZ-2-piperidinemethanol

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 396.4±25.0 °C at 760 mmHg
• 分子式: C₁₄H₁₉NO₃
• 分子量: 249.306
• 闪点: 193.5±23.2 °C
• 精确质量: 249.136490
• PSA: 49.77000
• LogP: 1.63
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.550
• 储存条件: 2-8°C，干燥，密封

安全

• 危害码 (欧洲): T

合成路线

501-53-1 3433-37-2 ~89% 105706-75-0

文献：Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Pittalis, Mario Synthetic Communications, 2007 , vol. 37, # 20 p. 3623 - 3634

1072344-35-4 ~% 105706-75-0

文献：WO2008/125570 A1, ; Page/Page column 35 ; WO 2008/125570 A1

180609-56-7 ~97% 105706-75-0

文献：Nurdinov, R.; Liepin'sh, E. E.; Kalvin'sh, I. Ya. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993 , vol. 29, # 11 p. 1352 - 1357 Khimiya Geterotsiklicheskikh Soedinenii, 1993 , # 11 p. 1567 - 1573

28697-07-6 ~% 105706-75-0

文献：Tetrahedron Letters, , vol. 43, # 48 p. 8759 - 8763

501-53-1 ~% 105706-75-0

文献：Tetrahedron Letters, , vol. 43, # 48 p. 8759 - 8763

4043-87-2 ~% 105706-75-0

文献：Tetrahedron Letters, , vol. 43, # 48 p. 8759 - 8763

35677-83-9 ~% 105706-75-0

文献：Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 29, # 11 p. 1352 - 1357 Khimiya Geterotsiklicheskikh Soedinenii, , # 11 p. 1567 - 1573

上下游产品

上游产品  7
501-53-1 3433-37-2 1072344-35-4 180609-56-7
28697-07-6 4043-87-2 35677-83-9
下游产品  6
3105-95-1 212557-00-1 28697-11-2 105706-76-1
42329-17-9 5985-99-9