2767-80-8

• 常用中文名：三(羟甲基)膦
• 常用英文名：phosphanetriyltrimethanol
• CAS号：2767-80-8
• 分子式：C₃H₉O₃P
• 分子量：124.076
• 相关类别： 有机原料 有机膦化合物
• 发布时间：2018-06-08 11:30:53
• 更新时间：2024-01-02 09:48:51

• 化学试剂

名称

• 中文名: 三(羟基甲基)磷化氢
• 英文名: bis(hydroxymethyl)phosphanylmethanol
• 中文别名: 三(羟甲基)膦
• 英文别名: Phosphinidynetrimethanol; Tris(hydroxymethyl)phosphine; Trimethylolphosphine; Phosphinetriyltrimethanol; phosphanetriyltrimethanol; EINECS 220-445-6; Tris-hydroxymethyl-phosphine; MFCD00055382; Methanol, 1,1',1''-phosphinidynetris-; Methanol,phosphinidynetris; Phosphinidynetrismethanol

物化性质

• 密度: 1.137 (estimate)
• 沸点: 311.7±37.0 °C at 760 mmHg
• 熔点: 48-56ºC(lit.)
• 分子式: C₃H₉O₃P
• 分子量: 124.076
• 闪点: 142.3±26.5 °C
• 精确质量: 124.028931
• PSA: 74.28000
• LogP: 0.02
• 外观性状: Powder, Crystals or Chunks | White to pale yellow
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 储存条件:

  密封储存，储存于阴凉、干燥的库房。

• 稳定性:

  避免与不相容材料，卤素，氧接触。与卤素，氧反应。

• 计算化学:

  1.疏水参数计算参考值（XlogP）:-1.8

  2.氢键供体数量:3

  3.氢键受体数量:3

  4.可旋转化学键数量:3

  5.互变异构体数量:无

  6.拓扑分子极性表面积60.7

  7.重原子数量:7

  8.表面电荷:0

  9.复杂度:31.7

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：白色结晶性粉末

  2. 密度（g/mL,25℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：48-56

  5. 沸点（ºC,常压）：111-113

  6. 沸点（ºC,33mmHg）：未确定

  7. 折射率(n20/D)：未确定

  8. 闪点（ºC）：＞110

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（mPa,20ºC）：未确定

  12. 饱和蒸气压（kPa,25ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：不溶于水

MSDS

Name: Tris(hydroxymethyl)phosphine Material Safety Data Sheet Synonym: CAS: 2767-80-8 Section 1 - Chemical Product MSDS Name:Tris(hydroxymethyl)phosphine Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 2767-80-8 Tris(hydroxymethyl)phosphine 220-445-6 Hazard Symbols: T Risk Phrases: 25 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Toxic if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. Toxic if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid immediately. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 2767-80-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: colorless Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Insoluble. Specific Gravity/Density: Molecular Formula: C3H9O3P Molecular Weight: 124.08 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, halogens, oxygen. Hazardous Decomposition Products: Carbon monoxide, oxides of phosphorus, carbon dioxide, formaldehyde. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 2767-80-8: PC3502500 LD50/LC50: CAS# 2767-80-8: Draize test, rabbit, eye: 100 uL/24H Severe; Draize test, rabbit, skin: 500 uL/24H Severe; Oral, rat: LD50 = 178 mg/kg. Carcinogenicity: Tris(hydroxymethyl)phosphine - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 25 Toxic if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 2767-80-8: No information available. Canada CAS# 2767-80-8 is listed on Canada's DSL List. CAS# 2767-80-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 2767-80-8 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 符号: GHS05, GHS06
• 信号词: Danger
• 危害声明: H301-H315-H318-H335
• 警示性声明: P261-P280-P301 + P310-P305 + P351 + P338
• 危害码 (欧洲): T
• 风险声明 (欧洲): 25
• 安全声明 (欧洲): S26;S45;S36/S37/S39
• 危险品运输编码: UN 2811 6.1/PG 3
• WGK德国: 3
• RTECS号: PC3502500
• 海关编码: 2905199090

合成路线

124-64-1 ~97% 2767-80-8

文献：Cristau, Henri-Jean; Virieux, David; Mouchet, Patrick; Fruchier, Alain European Journal of Organic Chemistry, 1999 , # 7 p. 1561 - 1569

124-64-1 ~0% 1067-12-5 2767-80-8

文献：Kisanga, Philip; Verkade, John Heteroatom Chemistry, 2001 , vol. 12, # 2 p. 114 - 117

50-00-0 ~% 2767-80-8

文献：Grinshtein,E.I. et al. J. Gen. Chem. USSR (Engl. Transl.), 1966 , vol. 36, # 2 p. 302 - 306,311 - 315

16980-25-9 ~% 1067-12-5 2767-80-8

文献：Volcko, E. J.; Verkade, J. G. Phosphorus and Sulfur and the Related Elements, 1984 , vol. 21, p. 111 - 118

上下游产品

上游产品  2
124-64-1 50-00-0
下游产品  7
24647-30-1 7650-89-7 53597-69-6 124-64-1
16111-57-2 1067-12-5 63245-87-4

海关

海关编码	2905199090
中文概述	2905199090. 其他饱和一元醇. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%