3615-24-5

• 常用中文名：异丙氨基比林
• 常用英文名：Ramifenazone
• CAS号：3615-24-5
• 分子式：C₁₄H₁₉N₃O
• 分子量：245.320
• 相关类别： 研究领域 炎症/免疫
• 发布时间：2018-03-07 08:00:00
• 更新时间：2024-01-09 11:32:02
• 【用途一】
  用作消炎镇痛药

名称

• 中文名: 异丙氨基比林
• 英文名: 1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one
• 中文别名: 1,2-二氢-1,5-二甲基-4-(异丙基氨基)-2-苯基-3H-吡唑-3-酮; 异比林
• 英文别名: 1,2-Dihydro-1,5-dimethyl-4-[(1-methylethyl)amino]-2-phenyl-3H-pyrazol-3-one; 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-[(1-methylethyl)amino]-2-phenyl-; Isopyrine; Isopropylaminoantipyrine; 4-Isopropylaminoantipyrine; Tomanol-wirkstoff; 4-(Isopropylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; EINECS 222-791-3; Isopirina; MFCD00800727; Isopropylaminophenazone; 4-isopropylaminophenazone; Ramifenazone; 1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)-1,2-dihydro-3H-pyrazol-3-one

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 348.5±45.0 °C at 760 mmHg
• 分子式: C₁₄H₁₉N₃O
• 分子量: 245.320
• 闪点: 164.6±28.7 °C
• 精确质量: 245.152817
• PSA: 38.96000
• LogP: 0.90
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.595
• 储存条件: 2-8℃

生物活性

• 描述: Ramifenazone是一种非甾体抗炎药。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CD2975000 CHEMICAL NAME : Antipyrine, 4-(isopropylamino)- CAS REGISTRY NUMBER : 3615-24-5 BEILSTEIN REFERENCE NO. : 0231936 LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C14-H19-N3-O MOLECULAR WEIGHT : 245.36 WISWESSER LINE NOTATION : T5NNVJ A1 BR& DMY1&1 E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 715 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,665,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 820 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,665,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1070 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 690 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,665,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 370 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 233,365,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 567 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1024,1970

安全

• 海关编码: 2933199090

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海关

海关编码	2933199090
中文概述	2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%