6954-48-9

• 常用中文名：1,2-Naphthalenedione,6-bromo-
• 常用英文名：1,2-Naphthalenedione,6-bromo-
• CAS号：6954-48-9
• 分子式：C₁₀H₅BrO₂
• 分子量：237.04900
• 发布时间：2016-05-02 14:47:19
• 更新时间：2025-08-26 11:44:24

名称

• 英文名: 6-bromonaphthalene-1,2-dione
• 英文别名: Bonaphthone; 6-bromo-1,2-naphthoqinone; 1,2-NAPHTHOQUINONE,6-BROMO; Bonaphthon; 6-BROMO-1,2-NAPHTHALENEDIONE; Bonafton

物化性质

• 密度: 1.708g/cm3
• 沸点: 363.7ºC at 760 mmHg
• 分子式: C₁₀H₅BrO₂
• 分子量: 237.04900
• 闪点: 147.5ºC
• 精确质量: 235.94700
• PSA: 34.14000
• LogP: 2.22770
• 折射率: 1.649

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QL7400000 CHEMICAL NAME : 1,2-Naphthoquinone, 6-bromo- CAS REGISTRY NUMBER : 6954-48-9 BEILSTEIN REFERENCE NO. : 1944551 LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C10-H5-Br-O2 MOLECULAR WEIGHT : 237.06 WISWESSER LINE NOTATION : L66 BVVJ HE HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 43,337,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,628,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 260 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,628,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,628,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >50 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Nutritional and Gross Metabolic - body temperature decrease REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,628,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,628,1976 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 700 mg/kg SEX/DURATION : female 12 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 41,109,1978

安全

• 海关编码: 2914700090

合成路线

15231-91-1 ~70% 6954-48-9

文献：Cui, Jia-Hua; Li, Shao-Shun Journal of the Chinese Chemical Society, 2013 , vol. 60, # 9 p. 1163 - 1168

16239-18-2 ~51% 6954-48-9

文献：Cell Therapeutics Europe S.R.L. Patent: US2009/36441 A1, 2009 ; Location in patent: Page/Page column 4 ;

13720-04-2 ~% 6954-48-9

文献：Journal fuer Praktische Chemie (Leipzig), , vol. <2>43, p. 59

135-19-3 ~% 6954-48-9

文献：Journal of the Chinese Chemical Society, , vol. 60, # 9 p. 1163 - 1168

上下游产品

上游产品  4
15231-91-1 16239-18-2 13720-04-2 135-19-3
下游产品  10
65249-23-2 50457-15-3 61983-29-7 61983-30-0
61983-31-1 61983-32-2 61983-34-4 61983-35-5
61983-36-6 61983-37-7

海关

海关编码	2914700090
中文概述	2914700090 其他酮及醌的卤化、磺化衍生物（包括硝化和亚硝化衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%