701-44-0

• 常用中文名：1-甲基-6-氧代-1,6-二氢吡啶-3-甲酰胺
• 常用英文名：1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
• CAS号：701-44-0
• 分子式：C₇H₈N₂O₂
• 分子量：152.151
• 相关类别： 研究领域 其他
• 发布时间：2018-12-29 17:43:11
• 更新时间：2025-08-23 18:21:19
• 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的最终产物之一。

名称

• 中文名: 1-甲基-6-氧代吡啶-3-甲酰胺
• 英文名: N-methyl-6-pyridone-3-carboxamide
• 英文别名: 1-methyl-2-pyridone-5-carboxamide; N'-Methyl-2-pyridone-5-carboxamide; 1-METHYL-6-OXO-PYRIDINE-3-CARBOXAMIDE; 1-methyl-6-oxopyridine-3-carboxamide; 3-Pyridinecarboxamide,1,6-dihydro-1-methyl-6-oxo; 1-Methyl-5-carboxylamide-2-pyridone; N1-Methyl-2-pyridone-5-carboxamide; N-methyl-6-pyridone-3-carboxamide; 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxamide; Nudifloramide; 3-Pyridinecarboxamide, 1,6-dihydro-1-methyl-6-oxo-; 1-methyl-1,6-dihydro-6-oxo-3-pyridinecarboxamide; 1-methyl-1,6-dihydro-6-oxo-pyridine-3-carboxylic acid; 1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxamide; 1-Methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 396.7±42.0 °C at 760 mmHg
• 熔点: 202-207ºC (dec.)
• 分子式: C₇H₈N₂O₂
• 分子量: 152.151
• 闪点: 193.7±27.9 °C
• 精确质量: 152.058578
• PSA: 65.09000
• LogP: -1.51
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.577
• 储存条件: 室温，干燥

生物活性

• 描述: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的最终产物之一。
• 相关类别:
  天然产物 >> 其他
  研究领域 >> 其他
• 靶点:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May;(84):S19-21.

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933399090

合成路线

107971-06-2 ~81% 701-44-0

文献：Buurman; Van der Plas Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018

10561-91-8 ~% 701-44-0

文献：Holman; Wiegand Biochemical Journal, 1948 , vol. 43, p. 423,425

1005-24-9 ~% 701-44-0

文献：Angelino, S.A.G.F.; Buurman, D.J.; Plas, H.C. van der; Mueller, F. Recueil: Journal of the Royal Netherlands Chemical Society, 1982 , vol. 101, # 10 p. 342 - 346

3719-45-7 ~% 701-44-0

文献：Bradlow; Vanderwerf Journal of Organic Chemistry, 1951 , vol. 16, p. 73,79 Show Details Holman; Wiegand Biochemical Journal, 1948 , vol. 43, p. 423,425 Show Details Huff Journal of Biological Chemistry, 1947 , vol. 171, p. 639

6456-44-6 ~% 701-44-0 769-09-5

文献：Pullman; Colowick Journal of Biological Chemistry, 1954 , vol. 206, p. 121,125

77837-12-8 ~% 701-44-0

文献：Plas, H. C. van der; Buurman, D. J. Tetrahedron Letters, 1984 , vol. 25, # 34 p. 3763 - 3764

上下游产品

上游产品  6
107971-06-2 10561-91-8 1005-24-9 3719-45-7
6456-44-6 77837-12-8
下游产品  1
768-45-6

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%