455957-94-5

• 常用中文名：(3S,4R)-1-叔丁基-4-(2,4-二氟苯基)吡咯烷-3-羧酸
• 常用英文名：(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid
• CAS号：455957-94-5
• 分子式：C₁₅H₁₉F₂NO₂
• 分子量：283.31400
• 发布时间：2018-12-24 15:42:36
• 更新时间：2025-08-29 11:03:49

名称

• 中文名: (3S,4R)-1-叔丁基-4-(2,4-二氟苯基)吡咯烷-3-羧酸
• 英文名: (3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid
• 英文别名: MFCD13152278

物化性质

• 分子式: C₁₅H₁₉F₂NO₂
• 分子量: 283.31400
• 精确质量: 283.13800
• PSA: 40.54000
• LogP: 2.80120
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

852305-06-7 ~% 455957-94-5

文献：Chung, John Y. L.; Cvetovich, Raymond; Amato, Joseph; McWilliams, J. Christopher; Reamer, Robert; DiMichele, Lisa Journal of Organic Chemistry, 2005 , vol. 70, # 9 p. 3592 - 3601

862283-30-5 ~% 455957-94-5

文献：Lansdell, Mark I.; Hepworth, David; Calabrese, Andrew; Brown, Alan D.; Blagg, Julian; Burring, Denise J.; Wilson, Peter; Fradet, David; Brown, T. Bruce; Quinton, Faye; Mistry, Neela; Tang, Kim; Mount, Natalie; Stacey, Peter; Edmunds, Nick; Adams, Cathryn; Gaboardi, Samantha; Neal-Morgan, Stevie; Wayman, Chris; Cole, Susan; Phipps, Joanne; Lewis, Mark; Verrier, Hugh; Gillon, Val; Feeder, Neil; Heatherington, Anne; Sultana, Stefan; Haughie, Scott; Martin, Steven W.; Sudworth, Maria; Tweedy, Sarah Journal of Medicinal Chemistry, 2010 , vol. 53, # 8 p. 3183 - 3197

794500-76-8 794500-77-9 ~% 455957-94-5

文献：MERCK and CO., INC. Patent: WO2004/92126 A2, 2004 ; Location in patent: Page 25; 31-32 ; WO 2004/092126 A2

455957-73-0 ~% 455957-94-5

文献：Lansdell, Mark I.; Hepworth, David; Calabrese, Andrew; Brown, Alan D.; Blagg, Julian; Burring, Denise J.; Wilson, Peter; Fradet, David; Brown, T. Bruce; Quinton, Faye; Mistry, Neela; Tang, Kim; Mount, Natalie; Stacey, Peter; Edmunds, Nick; Adams, Cathryn; Gaboardi, Samantha; Neal-Morgan, Stevie; Wayman, Chris; Cole, Susan; Phipps, Joanne; Lewis, Mark; Verrier, Hugh; Gillon, Val; Feeder, Neil; Heatherington, Anne; Sultana, Stefan; Haughie, Scott; Martin, Steven W.; Sudworth, Maria; Tweedy, Sarah Journal of Medicinal Chemistry, 2010 , vol. 53, # 8 p. 3183 - 3197

上下游产品

上游产品  3
852305-06-7 794500-76-8 794500-77-9
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%