263888-56-8

• 常用中文名：5-氰基异吲哚啉-2-羧酸叔丁酯
• 常用英文名：TERT-BUTYL 5-CYANOISOINDOLINE-2-CARBOXYLATE
• CAS号：263888-56-8
• 分子式：C₁₄H₁₆N₂O₂
• 分子量：244.28900
• 发布时间：2018-12-03 17:43:43
• 更新时间：2025-08-27 11:04:51

名称

• 中文名: 5-氰基异吲哚啉-2-羧酸叔丁酯
• 英文名: tert-butyl 5-cyano-1,3-dihydroisoindole-2-carboxylate
• 英文别名: N-t-butoxycarbonyl-5-cyanoisoindoline; TERT-BUTYL 5-CYANO-2,3-DIHYDRO-1H-ISOINDOLE-2-CARBOXYLATE; 2H-Isoindole-2-carboxylicacid,5-cyano-1,3-dihydro-,1,1-dimethylethyl ester; TERT-BUTYL 5-CYANOISOINDOLINE-2-CARBOXYLATE; N-(tert-Butoxycarbonyl)-5-cyanoisoindoline

物化性质

• 分子式: C₁₄H₁₆N₂O₂
• 分子量: 244.28900
• 精确质量: 244.12100
• PSA: 53.33000
• LogP: 2.74688

合成路线

557-21-1 263888-57-9 ~88% 263888-56-8

文献：Austin, Nigel E; Avenell, Kim Y; Boyfield, Izzy; Branch, Clive L; Hadley, Michael S; Jeffrey, Phillip; Johnson, Christopher N; Macdonald, Gregor J; Nash, David J; Riley, Graham J; Smith, Alexander B; Stemp, Geoffrey; Thewlis, Kevin M; Vong, Antonio K.K; Wood, Martyn D Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 685 - 688

685565-18-8 ~% 263888-56-8

文献：GLAXO GROUP LIMITED Patent: WO2004/37788 A1, 2004 ; Location in patent: Page 15 ; WO 2004/037788 A1

24424-99-5 ~% 263888-56-8

文献：Austin, Nigel E; Avenell, Kim Y; Boyfield, Izzy; Branch, Clive L; Hadley, Michael S; Jeffrey, Phillip; Johnson, Christopher N; Macdonald, Gregor J; Nash, David J; Riley, Graham J; Smith, Alexander B; Stemp, Geoffrey; Thewlis, Kevin M; Vong, Antonio K.K; Wood, Martyn D Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 685 - 688

127168-88-1 ~% 263888-56-8

文献：Austin, Nigel E; Avenell, Kim Y; Boyfield, Izzy; Branch, Clive L; Hadley, Michael S; Jeffrey, Phillip; Johnson, Christopher N; Macdonald, Gregor J; Nash, David J; Riley, Graham J; Smith, Alexander B; Stemp, Geoffrey; Thewlis, Kevin M; Vong, Antonio K.K; Wood, Martyn D Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 685 - 688

54544-67-1 ~% 263888-56-8

文献：Austin, Nigel E; Avenell, Kim Y; Boyfield, Izzy; Branch, Clive L; Hadley, Michael S; Jeffrey, Phillip; Johnson, Christopher N; Macdonald, Gregor J; Nash, David J; Riley, Graham J; Smith, Alexander B; Stemp, Geoffrey; Thewlis, Kevin M; Vong, Antonio K.K; Wood, Martyn D Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 685 - 688

226070-47-9 ~% 263888-56-8

文献：Austin, Nigel E; Avenell, Kim Y; Boyfield, Izzy; Branch, Clive L; Hadley, Michael S; Jeffrey, Phillip; Johnson, Christopher N; Macdonald, Gregor J; Nash, David J; Riley, Graham J; Smith, Alexander B; Stemp, Geoffrey; Thewlis, Kevin M; Vong, Antonio K.K; Wood, Martyn D Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 5 p. 685 - 688

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557-21-1 263888-57-9 685565-18-8 24424-99-5
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