376-50-1

• 常用中文名：全氟己二酸二乙酯
• 常用英文名：diethyl octafluoroadipate
• CAS号：376-50-1
• 分子式：C₁₀H₁₀F₈O₄
• 分子量：346.17100
• 发布时间：2018-03-03 08:00:00
• 更新时间：2024-01-02 16:17:35

名称

• 中文名: 全氟己二酸二乙酯
• 英文名: diethyl 2,2,3,3,4,4,5,5-octafluorohexanedioate
• 英文别名: Diethyl octafluoroadipate; Octafluor-adipinsaeure-diaethylester; Hexanedioic acid,octafluoro-,diethyl ester; diethyl perfluoroadipate; EINECS 206-810-2; Diethyl octafluorohexanedioate; octafluoro-hexanedioic acid diethyl ester; perfluoroadipic acid diethyl ester; octafluoro-adipic acid diethyl ester

物化性质

• 密度: 1.416g/cm3
• 沸点: 237.1ºC at 760mmHg
• 分子式: C₁₀H₁₀F₈O₄
• 分子量: 346.17100
• 闪点: 94.5ºC
• 精确质量: 346.04500
• PSA: 52.60000
• LogP: 2.65380
• 折射率: 1.353

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MO1953000 CHEMICAL NAME : Hexanedioic acid, octafluoro-, diethyl ester CAS REGISTRY NUMBER : 376-50-1 BEILSTEIN REFERENCE NO. : 1807886 LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C10-H10-F8-O4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >8400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,142,1971 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >200 mg/m3/4H TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS REFERENCE : TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,142,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/m3/13W-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Related to Chronic Data - death REFERENCE : TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,142,1971 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 mg/m3/17W-I TOXIC EFFECTS : Vascular - BP elevation not characterized in autonomic section Nutritional and Gross Metabolic - changes in chlorine REFERENCE : TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,142,1971 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 200 mg/m3/13W-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Blood - changes in leukocyte (WBC) count Related to Chronic Data - death REFERENCE : TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 12,142,1971

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): 36/37/38
• 海关编码: 2917190090

合成路线

64-17-5 336-08-3 ~76% 376-50-1

文献：Hudlicky, M. Journal of Fluorine Chemistry, 1981 , vol. 18, p. 383 - 406

64-17-5 37881-62-2 ~89% 376-50-1

文献：Hudlicky, M. Journal of Fluorine Chemistry, 1981 , vol. 18, p. 383 - 406

64-17-5 ~% 376-50-1

文献：Purdue Res. Found. Patent: US2453147 , 1946 ; Full Text Show Details McBee; Wiseman; Bachman Industrial and Engineering Chemistry, 1947 , vol. 39, p. 415,416

2367-86-4 ~% 376-50-1

文献：Roylance et al. Journal of the Chemical Society, 1954 , p. 4426,4428

上下游产品

上游产品  4
64-17-5 336-08-3 37881-62-2 2367-86-4
下游产品  2
355-66-8 355-74-8

海关

海关编码	2917190090
中文概述	2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%